Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4128895..4129040 Replicon chromosome
Accession NZ_CP039951
Organism Klebsiella pneumoniae strain 18KM2445b

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4128931..4129033 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4128895..4129040 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FC646_RS19645 4124025..4126085 + 2061 WP_004148850.1 oligopeptidase B -
FC646_RS19650 4126089..4126748 - 660 WP_032435029.1 exodeoxyribonuclease X -
FC646_RS19655 4126827..4127057 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FC646_RS19660 4127170..4127544 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FC646_RS19665 4127548..4128417 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
FC646_RS19670 4128434..4128772 + 339 WP_002911404.1 YebY family protein -
- 4128895..4129040 - 146 - - Antitoxin
- 4128931..4129033 + 103 - - Toxin
FC646_RS19675 4129408..4129551 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FC646_RS19680 4129656..4130624 - 969 WP_004151446.1 VirK/YbjX family protein -
FC646_RS19685 4130781..4131434 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
FC646_RS19690 4131431..4131622 - 192 WP_002911395.1 YebW family protein -
FC646_RS19695 4131720..4131959 - 240 WP_002911393.1 YebV family protein -
FC646_RS19700 4132075..4133508 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124637 NZ_CP039951:4128931-4129033 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT124637 NZ_CP039951:c4129040-4128895 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References