Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2021250..2021394 | Replicon | chromosome |
| Accession | NZ_CP039948 | ||
| Organism | Klebsiella pneumoniae strain 19KM57 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2021286..2021388 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2021250..2021394 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FC645_RS09945 | 2016380..2018440 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FC645_RS09950 | 2018444..2019103 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FC645_RS09955 | 2019182..2019412 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FC645_RS09960 | 2019525..2019899 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FC645_RS09965 | 2019903..2020772 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| FC645_RS09970 | 2020789..2021127 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2021250..2021394 | - | 145 | - | - | Antitoxin |
| - | 2021286..2021388 | + | 103 | - | - | Toxin |
| FC645_RS09975 | 2021521..2021880 | - | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| FC645_RS09980 | 2021879..2022358 | + | 480 | WP_032419797.1 | lysis protein | - |
| FC645_RS09985 | 2023525..2024652 | + | 1128 | WP_064147220.1 | hypothetical protein | - |
| FC645_RS09990 | 2024902..2025330 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| FC645_RS09995 | 2025340..2025621 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T124612 NZ_CP039948:2021286-2021388 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT124612 NZ_CP039948:c2021394-2021250 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
