Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3259865..3260412 Replicon chromosome
Accession NZ_CP039934
Organism Myroides fluvii strain CJ210

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FBR08_RS14480 Protein ID WP_158963375.1
Coordinates 3259865..3260164 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FBR08_RS14485 Protein ID WP_158963376.1
Coordinates 3260161..3260412 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FBR08_RS14460 3255031..3255405 + 375 WP_158963371.1 rhodanese-like domain-containing protein -
FBR08_RS14465 3255484..3255774 + 291 WP_158963372.1 DUF4834 family protein -
FBR08_RS14470 3256049..3258475 + 2427 WP_158963373.1 YfhO family protein -
FBR08_RS14475 3258495..3259802 + 1308 WP_158963374.1 glycosyltransferase family 4 protein -
FBR08_RS14480 3259865..3260164 - 300 WP_158963375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FBR08_RS14485 3260161..3260412 - 252 WP_158963376.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FBR08_RS14490 3260882..3263692 - 2811 WP_158963377.1 excinuclease ABC subunit UvrA -
FBR08_RS14495 3263918..3264502 + 585 WP_158963378.1 sigma-70 family RNA polymerase sigma factor -
FBR08_RS16790 3264551..3264706 + 156 WP_199268607.1 hypothetical protein -
FBR08_RS14500 3264720..3265391 - 672 WP_158963379.1 endonuclease III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-67)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12179.99 Da        Isoelectric Point: 6.8799

>T124520 WP_158963375.1 NZ_CP039934:c3260164-3259865 [Myroides fluvii]
MKYKISKQAKLDLEQIWLYTFKEWSLEQADYYFDLLVNEMEYIADHPNLGKDYNEVRKGYFRSRVKSHFIFYKVNLLEEK
VEIIRILHQQMDVDSHINK

Download         Length: 300 bp

>T124520 NZ_CP039934:c3260164-3259865 [Myroides fluvii]
ATGAAATATAAGATTAGTAAACAAGCTAAACTTGATTTAGAACAAATTTGGCTTTACACTTTTAAAGAATGGTCCTTGGA
GCAAGCGGATTACTATTTTGACTTACTCGTAAATGAAATGGAATATATTGCTGATCATCCAAACTTAGGAAAAGATTATA
ATGAGGTGAGAAAAGGTTATTTCCGTTCAAGAGTAAAATCTCATTTTATATTCTACAAAGTCAATCTGCTAGAAGAAAAA
GTAGAAATCATAAGAATCTTACATCAACAAATGGATGTTGATTCTCATATCAATAAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9546.75 Da        Isoelectric Point: 6.4688

>AT124520 WP_158963376.1 NZ_CP039934:c3260412-3260161 [Myroides fluvii]
MAKNTSILLGDYFDDFINAQIKSGKYSSASEVVRAALRMFEHQETKKLALIKELQQGEESGFSPDFNREIFKQNLHKKYS
AEE

Download         Length: 252 bp

>AT124520 NZ_CP039934:c3260412-3260161 [Myroides fluvii]
ATGGCAAAAAACACTTCGATTTTATTGGGCGATTATTTCGACGATTTTATCAATGCACAAATAAAAAGTGGAAAATATTC
TTCTGCAAGTGAAGTTGTAAGAGCTGCTTTAAGAATGTTTGAACACCAAGAAACTAAAAAATTAGCCTTAATAAAGGAAC
TTCAGCAAGGAGAAGAATCTGGGTTTTCTCCTGATTTCAATCGCGAAATTTTTAAACAAAACCTACATAAAAAATATTCC
GCTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References