Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 19283..19793 Replicon plasmid pTG29392_2
Accession NZ_CP039932
Organism Acinetobacter baumannii strain TG29392

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EA667_RS19710 Protein ID WP_000827770.1
Coordinates 19283..19543 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EA667_RS19715 Protein ID WP_001024070.1
Coordinates 19533..19793 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EA667_RS19650 14314..15042 - 729 WP_001283390.1 XRE family transcriptional regulator -
EA667_RS19655 15197..15493 + 297 WP_001181556.1 hypothetical protein -
EA667_RS19660 15524..16171 + 648 WP_000919094.1 hypothetical protein -
EA667_RS19665 16168..16683 + 516 WP_000119773.1 hypothetical protein -
EA667_RS19670 16709..17179 + 471 WP_000224739.1 hypothetical protein -
EA667_RS19675 17172..17381 + 210 WP_000912547.1 hypothetical protein -
EA667_RS19680 17396..17674 + 279 WP_000587223.1 hypothetical protein -
EA667_RS19685 17671..18018 + 348 WP_000827933.1 hypothetical protein -
EA667_RS19690 18037..18243 + 207 WP_000801902.1 hypothetical protein -
EA667_RS19695 18236..18835 + 600 WP_000892963.1 hypothetical protein -
EA667_RS19700 18825..19091 + 267 WP_000312809.1 hypothetical protein -
EA667_RS19705 19088..19270 - 183 WP_000764644.1 hypothetical protein -
EA667_RS19710 19283..19543 - 261 WP_000827770.1 Txe/YoeB family addiction module toxin Toxin
EA667_RS19715 19533..19793 - 261 WP_001024070.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EA667_RS19725 20293..20679 + 387 WP_024432159.1 hypothetical protein -
EA667_RS19730 20911..21397 + 487 Protein_30 hypothetical protein -
EA667_RS19735 21394..21924 + 531 WP_000587898.1 DUF2829 domain-containing protein -
EA667_RS19740 21917..22384 + 468 WP_001123866.1 hypothetical protein -
EA667_RS19745 22444..22890 + 447 WP_000467408.1 hypothetical protein -
EA667_RS19750 22883..23134 + 252 WP_001087198.1 hypothetical protein -
EA667_RS19755 23115..23645 + 531 WP_000219384.1 TIGR02594 family protein -
EA667_RS19760 23719..24387 + 669 WP_000037012.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..55269 55269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10117.52 Da        Isoelectric Point: 8.4866

>T124519 WP_000827770.1 NZ_CP039932:c19543-19283 [Acinetobacter baumannii]
MKRNIDFTPTAWDDYLYWQNQDKKTLKRINALIKDCQREPFSGIGKPEGLLGDLSGFWSRRIDEKNRLVYAVDDAAITII
SCRHHY

Download         Length: 261 bp

>T124519 NZ_CP039932:c19543-19283 [Acinetobacter baumannii]
ATGAAACGTAATATCGACTTCACCCCTACTGCTTGGGATGATTATTTATATTGGCAAAACCAAGACAAAAAGACGTTAAA
ACGTATTAATGCATTGATTAAAGATTGCCAACGTGAACCATTTAGTGGAATTGGCAAGCCTGAGGGTCTTCTAGGTGATT
TGTCTGGATTCTGGAGCAGACGAATAGATGAAAAAAACCGCTTGGTTTATGCCGTGGATGATGCCGCTATTACAATTATT
TCCTGCAGACACCATTACTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9656.75 Da        Isoelectric Point: 4.4067

>AT124519 WP_001024070.1 NZ_CP039932:c19793-19533 [Acinetobacter baumannii]
MNILTYSEARNNLKEVIDQVINDADVTVITRREGQDAVVMGLDHYNSMVETLYLLSNPANSAHLAKSISEYRANKATTRD
LIDDET

Download         Length: 261 bp

>AT124519 NZ_CP039932:c19793-19533 [Acinetobacter baumannii]
ATGAACATACTGACTTACAGCGAGGCGAGAAATAATCTCAAAGAGGTTATAGATCAGGTGATTAATGATGCTGACGTGAC
TGTAATTACTAGACGAGAAGGACAGGATGCAGTTGTAATGGGTTTAGATCATTACAATAGTATGGTTGAAACACTATACC
TACTTTCAAATCCAGCTAATTCGGCTCACTTAGCAAAATCAATCTCCGAGTACCGCGCTAATAAAGCAACTACGAGAGAT
TTAATTGACGATGAAACGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References