Detailed information of TA system TA124517

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 3961957..3962501
• Replicon: chromosome
• Accession: NZ_CP039928
• Organism: Shewanella sp. MEBiC00475

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FCN25_RS17565
• Protein ID: WP_137226695.1
• Coordinates: 3962202..3962501 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FCN25_RS17560
• Protein ID: WP_137226694.1
• Coordinates: 3961957..3962214 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FCN25_RS17540	3957365..3957895	+	531	WP_137226691.1	hypothetical protein	-
FCN25_RS17545	3958413..3959741	+	1329	WP_137226692.1	DASS family sodium-coupled anion symporter	-
FCN25_RS17550	3960459..3961052	+	594	WP_137226693.1	peptide-methionine (S)-S-oxide reductase MsrA	-
FCN25_RS17560	3961957..3962214	+	258	WP_137226694.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FCN25_RS17565	3962202..3962501	+	300	WP_137226695.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FCN25_RS17575	3963334..3963924	+	591	WP_137227460.1	hypothetical protein	-
FCN25_RS17580	3964148..3965083	-	936	WP_137226696.1	LysR family transcriptional regulator	-
FCN25_RS17585	3965208..3966233	+	1026	WP_137226697.1	zinc-binding alcohol dehydrogenase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11662.72 Da
• Isoelectric Point: 6.4671

>T124517 WP_137226695.1 NZ_CP039928:3962202-3962501 [Shewanella sp. MEBiC00475]
MAEIIWTNPALEDLNDIAEYIALSHMISAKKLVVKIFDNVERLEAFPESGKKPIELSNLNYREVVVNPCRIFYKVETDKV
YILHVMRQERDLRKFLLLL

Nucleotide

• Length: 300 bp

>T124517 NZ_CP039928:3962202-3962501 [Shewanella sp. MEBiC00475]
ATGGCTGAAATAATTTGGACAAACCCTGCACTAGAGGATCTGAATGATATAGCTGAATATATTGCTTTGAGTCATATGAT
ATCAGCTAAAAAGTTAGTGGTTAAAATATTCGATAATGTTGAACGACTTGAAGCGTTTCCTGAATCAGGCAAGAAACCAA
TAGAGTTAAGTAATCTTAACTATCGAGAGGTTGTCGTTAACCCATGTCGCATATTTTATAAAGTAGAGACCGATAAGGTT
TATATTTTACACGTCATGAGACAAGAGCGTGACTTGCGAAAATTTTTATTGCTGTTGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9747.30 Da
• Isoelectric Point: 7.2039

>AT124517 WP_137226694.1 NZ_CP039928:3961957-3962214 [Shewanella sp. MEBiC00475]
MRVELVTTLKRQATKILSELHSSKEPVLITEHGQPSAYLVDVDDFEFMQKRMQILEALAKGEQAISRGDTMSNVEAKEKM
NKWLK

Nucleotide

• Length: 258 bp

>AT124517 NZ_CP039928:3961957-3962214 [Shewanella sp. MEBiC00475]
ATGAGAGTAGAACTAGTAACAACACTGAAACGTCAAGCAACGAAAATATTGTCTGAGCTCCACTCTTCTAAAGAGCCGGT
CTTAATTACTGAGCATGGACAGCCTTCTGCATATCTTGTAGATGTTGACGATTTCGAATTTATGCAAAAACGTATGCAAA
TTCTTGAGGCTCTTGCTAAAGGTGAGCAGGCAATAAGTCGCGGAGATACTATGTCTAATGTTGAAGCGAAAGAGAAAATG
AATAAATGGCTGAAATAA