Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 12719..13404 Replicon plasmid pAtCFBP5875
Accession NZ_CP039896
Organism Rhizobium pusense strain CFBP5875

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CFBP5875_RS23325 Protein ID WP_137070079.1
Coordinates 12719..13141 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CFBP5875_RS23330 Protein ID WP_113731730.1
Coordinates 13138..13404 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5875_RS23300 8387..8857 + 471 WP_006699334.1 hypothetical protein -
CFBP5875_RS23305 8929..9695 + 767 WP_137070077.1 IS5 family transposase -
CFBP5875_RS23310 10009..10412 - 404 Protein_10 AAA family ATPase -
CFBP5875_RS23315 10497..11642 - 1146 WP_167497283.1 site-specific integrase -
CFBP5875_RS23320 12037..12681 - 645 WP_113731735.1 hypothetical protein -
CFBP5875_RS23325 12719..13141 - 423 WP_137070079.1 type II toxin-antitoxin system VapC family toxin Toxin
CFBP5875_RS23330 13138..13404 - 267 WP_113731730.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CFBP5875_RS23335 13492..14625 - 1134 WP_137070080.1 site-specific integrase -
CFBP5875_RS23340 14750..15703 + 954 WP_137070081.1 DUF1403 family protein -
CFBP5875_RS23345 15700..16416 + 717 WP_137070082.1 SMC-Scp complex subunit ScpB -
CFBP5875_RS23350 16426..17073 - 648 WP_137070083.1 hypothetical protein -
CFBP5875_RS23360 17276..17886 - 611 Protein_19 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..129573 129573
- flank IS/Tn - - 17258..17542 284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15585.91 Da        Isoelectric Point: 4.9702

>T124513 WP_137070079.1 NZ_CP039896:c13141-12719 [Rhizobium pusense]
MRLLLDTNVLSEVTKPRPDEAVLKWLHGLDEDRTFISIVSIAEIRRGIALMDSGRKRDSLDEWLAHDLPQRFESRILPVE
GPVALAWGDLMALAKRNGRGLASMDGLIAATAVAHQLTLATRNTKDFEGFGIDIIDPWVD

Download         Length: 423 bp

>T124513 NZ_CP039896:c13141-12719 [Rhizobium pusense]
ATGAGGCTGCTTCTGGATACGAACGTTCTGTCGGAAGTTACGAAACCTCGCCCGGATGAAGCTGTTCTTAAGTGGCTTCA
CGGGCTGGACGAAGACCGTACGTTCATCAGCATCGTGTCGATCGCTGAAATTCGGCGAGGCATTGCGTTGATGGATAGCG
GGCGAAAACGCGATTCCCTGGACGAATGGCTCGCGCATGATCTGCCTCAACGCTTCGAAAGCAGGATTTTGCCGGTGGAA
GGGCCTGTCGCCTTGGCCTGGGGCGATCTCATGGCGCTTGCCAAGCGAAATGGTCGGGGGCTTGCCTCGATGGACGGTCT
GATTGCCGCTACGGCCGTCGCCCATCAGCTAACGCTTGCGACGCGCAACACCAAGGATTTCGAAGGCTTTGGAATAGACA
TCATCGACCCATGGGTGGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9773.01 Da        Isoelectric Point: 6.4673

>AT124513 WP_113731730.1 NZ_CP039896:c13404-13138 [Rhizobium pusense]
MQTSTHDDMSWTVAGAKAKLSEVMERAQLAPQTITRNGKPSVVVVSAEEWQRKTGRRGSLAEFLLASPLRGADLDLERQH
DEPRDLSL

Download         Length: 267 bp

>AT124513 NZ_CP039896:c13404-13138 [Rhizobium pusense]
ATGCAAACATCAACCCACGACGATATGAGTTGGACGGTCGCCGGCGCAAAGGCAAAGCTCTCGGAAGTCATGGAGCGCGC
GCAATTGGCACCTCAGACGATTACACGCAACGGAAAGCCGAGCGTGGTCGTCGTTTCCGCAGAAGAGTGGCAGCGGAAAA
CTGGGCGCAGGGGATCGCTCGCGGAATTTCTGTTGGCATCGCCTCTACGCGGCGCGGATCTGGATCTTGAACGGCAGCAC
GACGAGCCACGTGACTTGTCGTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References