Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 637612..638219 Replicon chromosome
Accession NZ_CP039894
Organism Rhizobium pusense strain CFBP5875

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CFBP5875_RS03260 Protein ID WP_137068472.1
Coordinates 637612..637947 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFBP5875_RS03265 Protein ID WP_137069197.1
Coordinates 637944..638219 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5875_RS03245 633663..635855 - 2193 WP_006700077.1 penicillin-binding protein -
CFBP5875_RS03250 636109..636588 + 480 WP_003497144.1 YcgN family cysteine cluster protein -
CFBP5875_RS03255 636759..637583 + 825 WP_037091572.1 class D beta-lactamase -
CFBP5875_RS03260 637612..637947 - 336 WP_137068472.1 type II toxin-antitoxin system YafQ family toxin Toxin
CFBP5875_RS03265 637944..638219 - 276 WP_137069197.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CFBP5875_RS03270 638327..638935 + 609 WP_137068473.1 class I SAM-dependent methyltransferase -
CFBP5875_RS03275 639002..639382 + 381 WP_137068474.1 DUF1232 domain-containing protein -
CFBP5875_RS03280 639432..642017 + 2586 WP_167497109.1 heavy metal translocating P-type ATPase -
CFBP5875_RS03285 642014..642436 + 423 WP_004440702.1 Cu(I)-responsive transcriptional regulator -
CFBP5875_RS03290 642483..642683 + 201 WP_006700082.1 heavy-metal-associated domain-containing protein -
CFBP5875_RS03295 642864..643073 + 210 WP_137068475.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(22-111)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12896.71 Da        Isoelectric Point: 8.1030

>T124511 WP_137068472.1 NZ_CP039894:c637947-637612 [Rhizobium pusense]
VTEKKGHGKDAASKITVLPRSTDFTRQFIKDWQRLNNSGRYDMVKLKETMLLLIANDAPLPAQFRDHELTGEWRDHRECH
VGGDFLLIYTLDEKQNLLIFTRAGTHAELFR

Download         Length: 336 bp

>T124511 NZ_CP039894:c637947-637612 [Rhizobium pusense]
GTGACCGAGAAGAAGGGCCATGGAAAGGACGCAGCATCAAAGATAACGGTGCTGCCGCGCAGTACGGATTTTACCAGGCA
ATTTATCAAGGACTGGCAACGGCTGAACAATTCCGGGCGTTACGACATGGTGAAGCTGAAGGAGACCATGCTCCTTCTGA
TTGCAAACGACGCGCCGTTACCGGCCCAGTTTCGTGACCATGAACTGACCGGAGAATGGCGTGATCATCGCGAATGCCAT
GTCGGCGGGGACTTTCTGTTGATCTACACTCTCGATGAGAAGCAGAACCTTCTCATCTTCACCCGCGCTGGAACGCACGC
CGAGCTCTTCAGGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10039.54 Da        Isoelectric Point: 6.3402

>AT124511 WP_137069197.1 NZ_CP039894:c638219-637944 [Rhizobium pusense]
MTANAYVRARIDQTLKDDATAVLDSLGLTISDVMRMMLTRIAREKALPIELTQPSAETLAAIEEARAIAASRRSRFDTTE
ALFDALDGKKR

Download         Length: 276 bp

>AT124511 NZ_CP039894:c638219-637944 [Rhizobium pusense]
ATGACCGCAAATGCTTATGTAAGAGCGCGCATCGATCAGACACTCAAGGATGACGCGACGGCCGTGCTGGACAGTCTGGG
ACTTACCATTTCCGATGTCATGCGAATGATGCTCACGCGCATTGCGCGAGAAAAAGCTCTGCCGATAGAACTGACGCAAC
CAAGTGCCGAAACCCTCGCTGCAATTGAAGAAGCGCGCGCCATCGCTGCTTCCAGGCGCAGTCGTTTCGATACGACGGAA
GCACTATTTGACGCCCTTGATGGTAAAAAGAGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References