Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 503969..504513 Replicon chromosome
Accession NZ_CP039894
Organism Rhizobium pusense strain CFBP5875

Toxin (Protein)


Gene name parE Uniprot ID U4PRC3
Locus tag CFBP5875_RS02505 Protein ID WP_004440407.1
Coordinates 504223..504513 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID U4PRA7
Locus tag CFBP5875_RS02500 Protein ID WP_022555750.1
Coordinates 503969..504220 (+) Length 84 a.a.

Genomic Context

CFBP5875_RS02475CFBP5875_RS02480CFBP5875_RS02495CFBP5875_RS02500CFBP5875_RS02505CFBP5875_RS02520CFBP5875_RS02525CFBP5875_RS02470CFBP5875_RS02485CFBP5875_RS02510CFBP5875_RS02515
Location: 499971..500651 (681 bp)
Type: Others
Protein ID: WP_137068417.1
Location: 500692..501153 (462 bp)
Type: Others
Protein ID: WP_072494876.1
Location: 502450..503595 (1146 bp)
Type: Others
Protein ID: WP_004440405.1
Location: 503969..504220 (252 bp)
Type: Antitoxin
Protein ID: WP_022555750.1
Location: 504223..504513 (291 bp)
Type: Toxin
Protein ID: WP_004440407.1
Location: 506354..506881 (528 bp)
Type: Others
Protein ID: WP_137068419.1
Location: 507010..507690 (681 bp)
Type: Others
Protein ID: WP_006309853.1
Location: 499067..499756 (690 bp)
Type: Others
Protein ID: WP_003520496.1
Location: 501113..502213 (1101 bp)
Type: Others
Protein ID: WP_137068418.1
Location: 504545..505156 (612 bp)
Type: Others
Protein ID: WP_022555751.1
Location: 505153..506256 (1104 bp)
Type: Others
Protein ID: WP_112766510.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFBP5875_RS02470499067..499756-690WP_003520496.1HAD family hydrolase-
CFBP5875_RS02475499971..500651+681WP_137068417.1GntR family transcriptional regulator-
CFBP5875_RS02480500692..501153+462WP_072494876.1DUF1284 domain-containing protein-
CFBP5875_RS02485501113..502213-1101WP_137068418.1hypothetical protein-
CFBP5875_RS02495502450..503595+1146WP_004440405.1site-specific DNA-methyltransferase-
CFBP5875_RS02500503969..504220+252WP_022555750.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
CFBP5875_RS02505504223..504513+291WP_004440407.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CFBP5875_RS02510504545..505156-612WP_022555751.1HAD family phosphatase-
CFBP5875_RS02515505153..506256-1104WP_112766510.1A/G-specific adenine glycosylase-
CFBP5875_RS02520506354..506881+528WP_137068419.1DUF721 domain-containing protein-
CFBP5875_RS02525507010..507690+681WP_006309853.1DsbA family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(2-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11253.77 Da        Isoelectric Point: 6.6456

>T124510 WP_004440407.1 NZ_CP039894:504223-504513 [Rhizobium pusense]
MGFRLSLPAEEDVIRIAQEGIDLFGPQQARKYHRELFAIFDLISRNPRIARERNELSPSVRIHPFRAHLVVYRVEADDDV
LIVRVRHGHEDWGNEP

Download         Length: 291 bp

>T124510 NZ_CP039894:504223-504513 [Rhizobium pusense]
ATGGGATTTCGCCTTTCTCTGCCTGCGGAAGAAGACGTCATCCGCATAGCGCAAGAAGGCATCGACCTATTTGGACCTCA
GCAAGCGCGAAAGTACCATCGCGAACTTTTCGCAATATTCGACTTGATATCACGGAATCCGAGGATCGCACGCGAGCGTA
ACGAGTTGTCGCCGTCGGTGCGCATTCATCCGTTCAGAGCACATCTGGTGGTCTATCGCGTTGAGGCGGACGACGACGTC
CTCATCGTCCGCGTCCGCCATGGGCACGAGGACTGGGGCAATGAGCCTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9316.56 Da        Isoelectric Point: 6.9801

>AT124510 WP_022555750.1 NZ_CP039894:503969-504220 [Rhizobium pusense]
MVTMNISLPGQMKEWVEAQSKTGRYSNASDYVRDLIRKDQERSEKIAAMQGLVDEGLQAPSGHRCEDALFAEAEARSMKR
KIG

Download         Length: 252 bp

>AT124510 NZ_CP039894:503969-504220 [Rhizobium pusense]
ATGGTGACCATGAATATTTCGCTGCCCGGCCAGATGAAGGAATGGGTCGAAGCGCAGTCTAAAACGGGCCGTTACTCCAA
TGCCAGCGACTATGTCCGAGATCTCATCCGAAAGGATCAGGAGCGGAGCGAAAAGATCGCTGCCATGCAGGGTCTGGTGG
ACGAAGGATTGCAGGCTCCCTCCGGTCATCGTTGTGAAGATGCCTTGTTTGCTGAGGCCGAAGCCCGCTCCATGAAACGT
AAAATTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBU4PRC3

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A098RRB9

References