Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 4542842..4543425 Replicon chromosome
Accession NZ_CP039844
Organism Providencia rettgeri strain Pr-15-2-50

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FCT01_RS21050 Protein ID WP_096863599.1
Coordinates 4543123..4543425 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FCT01_RS21045 Protein ID WP_004265229.1
Coordinates 4542842..4543126 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCT01_RS21020 4538002..4538979 - 978 WP_004265237.1 6-phosphofructokinase -
FCT01_RS21025 4539386..4540330 - 945 WP_004265235.1 phosphatidate cytidylyltransferase -
FCT01_RS21030 4540327..4540968 - 642 WP_094961883.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
FCT01_RS21035 4541206..4541958 - 753 WP_004265231.1 M48 family metallopeptidase -
FCT01_RS21040 4542178..4542759 - 582 WP_094961882.1 HutD family protein -
FCT01_RS21045 4542842..4543126 - 285 WP_004265229.1 putative addiction module antidote protein Antitoxin
FCT01_RS21050 4543123..4543425 - 303 WP_096863599.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FCT01_RS21055 4543682..4544251 - 570 WP_110592812.1 Spy/CpxP family protein refolding chaperone -
FCT01_RS21060 4544402..4545100 + 699 WP_004265224.1 envelope stress response regulator transcription factor CpxR -
FCT01_RS21065 4545097..4546467 + 1371 WP_004265222.1 envelope stress sensor histidine kinase CpxA -
FCT01_RS21070 4546939..4548375 + 1437 WP_110592811.1 capsule assembly Wzi family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11433.37 Da        Isoelectric Point: 10.0723

>T124372 WP_096863599.1 NZ_CP039844:c4543425-4543123 [Providencia rettgeri]
MITVLTTECFDSWIKNLRDIRAKTKILMRIRRLKNGNYGDVQPIGDGFSELRVHEGQGYRVYLKQKNNVIVILLCGGTKA
TQQKDIHKAKLLFGEVEGEL

Download         Length: 303 bp

>T124372 NZ_CP039844:c4543425-4543123 [Providencia rettgeri]
ATGATCACGGTTCTAACAACGGAATGTTTTGATAGTTGGATCAAAAATCTTAGAGATATTCGAGCTAAAACTAAAATTCT
AATGAGAATTAGGCGGTTAAAAAATGGAAATTATGGTGATGTTCAACCCATTGGTGATGGCTTTTCGGAACTGAGGGTAC
ATGAAGGACAAGGGTATCGTGTTTATCTAAAGCAGAAAAACAATGTTATTGTAATTTTACTTTGTGGTGGGACAAAGGCA
ACGCAGCAGAAGGATATCCATAAAGCTAAACTTCTTTTTGGTGAAGTTGAGGGGGAACTATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10454.13 Da        Isoelectric Point: 4.5983

>AT124372 WP_004265229.1 NZ_CP039844:c4543126-4542842 [Providencia rettgeri]
MNTKLKEFDIAEYLNSEEEIQMYLNEILEEGDPSLVLAALGDIAKARNMSQLAKEVGMSREGLYKALSGQGNPTFMTIIK
IVNSLGLKLQFKSI

Download         Length: 285 bp

>AT124372 NZ_CP039844:c4543126-4542842 [Providencia rettgeri]
ATGAATACTAAATTAAAAGAATTTGATATCGCTGAGTATTTAAACAGTGAAGAAGAAATACAAATGTATCTAAACGAAAT
TCTAGAAGAAGGTGACCCTAGTCTAGTTCTCGCTGCACTTGGTGATATTGCGAAGGCAAGAAATATGAGCCAATTAGCTA
AAGAAGTTGGAATGAGTCGTGAAGGTTTATATAAGGCGCTATCAGGACAGGGAAATCCAACATTTATGACGATTATAAAA
ATCGTTAATTCTCTCGGATTAAAGCTACAGTTTAAGAGTATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References