Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4046816..4047612 Replicon chromosome
Accession NZ_CP039844
Organism Providencia rettgeri strain Pr-15-2-50

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag FCT01_RS18680 Protein ID WP_110591148.1
Coordinates 4046816..4047328 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag FCT01_RS18685 Protein ID WP_102138080.1
Coordinates 4047325..4047612 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCT01_RS18665 4042868..4043839 - 972 WP_004259232.1 DNA-binding transcriptional regulator DsdC -
FCT01_RS18670 4044057..4045393 + 1337 Protein_3659 D-serine transporter DsdX -
FCT01_RS18675 4045406..4046740 + 1335 WP_094961592.1 D-serine ammonia-lyase -
FCT01_RS18680 4046816..4047328 - 513 WP_110591148.1 GNAT family N-acetyltransferase Toxin
FCT01_RS18685 4047325..4047612 - 288 WP_102138080.1 DUF1778 domain-containing protein Antitoxin
FCT01_RS18690 4047855..4048916 - 1062 WP_110591147.1 osmoprotectant NAGGN system M42 family peptidase -
FCT01_RS18695 4048921..4049691 - 771 WP_004259240.1 FadR family transcriptional regulator -
FCT01_RS18700 4049722..4050525 - 804 WP_110591146.1 ABC transporter ATP-binding protein -
FCT01_RS18705 4050525..4052339 - 1815 WP_110591145.1 dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(32-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18348.23 Da        Isoelectric Point: 9.9566

>T124370 WP_110591148.1 NZ_CP039844:c4047328-4046816 [Providencia rettgeri]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKNRAMSNQNSGASRTFVTTSDNQVMGYYALSTGVVSTNQAVGRFRRNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGVVVHALTDNAKRFYEHIGFVPSPLDSMMLMITLAD
LQFALGIHPN

Download         Length: 513 bp

>T124370 NZ_CP039844:c4047328-4046816 [Providencia rettgeri]
ATGACATTGAAGCTAACAGCGCCAGAACCACTAAAAACAGGCCATTTACTGGAAGGGTTTTCCTCTGGTGAAGAGGCATT
GGATCTCTGGTTAAAAAACCGGGCAATGAGTAATCAAAACTCAGGGGCCTCGCGCACTTTTGTGACCACTTCGGATAACC
AAGTAATGGGTTACTATGCCTTGTCCACCGGGGTTGTGAGCACCAATCAAGCCGTTGGACGATTTCGCCGCAACATGCCC
TCTGACATTCCCGTCATCTTACTCGGCAGGCTAGCTGTAGATACAAGGGCGAAAGGTCTTGGAGTTGGTAGGGGGTTAGT
TAAAGATGCCTGTCATCGTGTTATTCAGGCTTCTGGGCTGGTGGGCATTCGAGGGGTTGTGGTTCACGCATTAACGGACA
ATGCTAAACGGTTCTATGAGCACATTGGTTTCGTCCCTTCACCACTTGACTCTATGATGTTGATGATAACGCTTGCCGAT
CTACAATTCGCATTGGGTATTCACCCGAACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10607.97 Da        Isoelectric Point: 4.8660

>AT124370 WP_102138080.1 NZ_CP039844:c4047612-4047325 [Providencia rettgeri]
MSTQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSAEVYQEFISQLDAAPSSN
EALRKTMMSKSPWEE

Download         Length: 288 bp

>AT124370 NZ_CP039844:c4047612-4047325 [Providencia rettgeri]
ATGTCGACTCAAAATGATGTTGCCGTGACTCGCTCATCTCTTAACCTGAGAATAAAACCGGAAGACAAAATCCTGATCGA
CCGTGCTGCGAATGCTGTGGGAAAAAACCGTACTGAATTTGTTCTGGAAGCGGCGCGGCGTGCAGCTGAAGAAACGCTGG
CCGATCTGCGGGTGATTAACGTCAGCGCCGAGGTTTACCAAGAATTTATCAGCCAGCTTGATGCCGCGCCTAGTAGTAAT
GAGGCATTGAGGAAAACGATGATGTCTAAATCCCCTTGGGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References