Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2338244..2338515 Replicon chromosome
Accession NZ_CP039837
Organism Escherichia coli O157:H7 strain USDA5905

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2338374..2338477 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2338244..2338515 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3175_RS11520 2334799..2335461 - 663 WP_000944256.1 exodeoxyribonuclease X -
E3175_RS11525 2335485..2336141 - 657 WP_000011661.1 carbon-nitrogen hydrolase family protein -
E3175_RS11530 2336243..2336473 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E3175_RS11535 2336612..2336986 + 375 WP_000168751.1 CopC domain-containing protein YobA -
E3175_RS11540 2336990..2337862 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
E3175_RS11545 2337875..2338216 + 342 WP_000976483.1 YebY family protein -
- 2338244..2338515 - 272 - - Antitoxin
- 2338374..2338477 + 104 - - Toxin
E3175_RS11550 2338612..2339268 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
E3175_RS11555 2339269..2339460 - 192 WP_001296140.1 YebW family protein -
E3175_RS11560 2339565..2339801 - 237 WP_001359800.1 DUF1480 family protein -
E3175_RS11565 2339919..2341358 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T124344 NZ_CP039837:2338374-2338477 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT124344 NZ_CP039837:c2338515-2338244 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References