Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2293650..2293921 Replicon chromosome
Accession NZ_CP039834
Organism Escherichia coli O157:H7 strain MB41-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2293780..2293883 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2293650..2293921 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCV42_RS11515 2290205..2290867 - 663 WP_000944243.1 exodeoxyribonuclease X -
FCV42_RS11520 2290891..2291547 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
FCV42_RS11525 2291649..2291879 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FCV42_RS11530 2292018..2292392 + 375 WP_000168751.1 CopC domain-containing protein YobA -
FCV42_RS11535 2292396..2293268 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
FCV42_RS11540 2293281..2293622 + 342 WP_000976483.1 YebY family protein -
- 2293650..2293921 - 272 - - Antitoxin
- 2293780..2293883 + 104 - - Toxin
FCV42_RS11545 2294018..2294674 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
FCV42_RS11550 2294675..2294866 - 192 WP_001296140.1 YebW family protein -
FCV42_RS11555 2294971..2295207 - 237 WP_001295499.1 DUF1480 family protein -
FCV42_RS11560 2295325..2296764 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T124313 NZ_CP039834:2293780-2293883 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT124313 NZ_CP039834:c2293921-2293650 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References