Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2177244..2177389 Replicon chromosome
Accession NZ_CP039819
Organism Klebsiella pneumoniae strain C2414

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2177280..2177382 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2177244..2177389 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FA958_RS10915 2172374..2174434 + 2061 WP_004151449.1 oligopeptidase B -
FA958_RS10920 2174438..2175097 - 660 WP_002911407.1 exodeoxyribonuclease X -
FA958_RS10925 2175176..2175406 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FA958_RS10930 2175519..2175893 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FA958_RS10935 2175897..2176766 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FA958_RS10940 2176783..2177121 + 339 WP_002911404.1 YebY family protein -
- 2177244..2177389 - 146 - - Antitoxin
- 2177280..2177382 + 103 - - Toxin
FA958_RS10945 2177757..2177900 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FA958_RS10950 2178005..2178973 - 969 WP_004151446.1 VirK/YbjX family protein -
FA958_RS10955 2179130..2179783 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
FA958_RS10960 2179780..2179971 - 192 WP_002911395.1 YebW family protein -
FA958_RS10965 2180069..2180308 - 240 WP_002911393.1 YebV family protein -
FA958_RS10970 2180424..2181857 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124282 NZ_CP039819:2177280-2177382 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT124282 NZ_CP039819:c2177389-2177244 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References