Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2022196..2022343 Replicon chromosome
Accession NZ_CP039791
Organism Klebsiella quasipneumoniae strain C3001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022237..2022339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2022196..2022343 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FA956_RS09995 2017331..2019391 + 2061 WP_101861959.1 oligopeptidase B -
FA956_RS10000 2019395..2020054 - 660 WP_101861958.1 exodeoxyribonuclease X -
FA956_RS10005 2020133..2020363 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FA956_RS10010 2020476..2020850 + 375 WP_101861957.1 CopC domain-containing protein YobA -
FA956_RS10015 2020854..2021723 + 870 WP_101861956.1 copper homeostasis membrane protein CopD -
FA956_RS10020 2021740..2022078 + 339 WP_002911404.1 YebY family protein -
- 2022196..2022343 - 148 - - Antitoxin
- 2022237..2022339 + 103 - - Toxin
FA956_RS10025 2022718..2022861 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
FA956_RS10030 2022962..2023930 - 969 WP_072413392.1 VirK/YbjX family protein -
FA956_RS10035 2024087..2024740 + 654 WP_023290232.1 protein-serine/threonine phosphatase -
FA956_RS10040 2024737..2024928 - 192 WP_002911395.1 YebW family protein -
FA956_RS10045 2025026..2025265 - 240 WP_002911393.1 YebV family protein -
FA956_RS10050 2025381..2026811 - 1431 WP_044523969.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T124236 NZ_CP039791:2022237-2022339 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT124236 NZ_CP039791:c2022343-2022196 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References