Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 1840112..1840629 | Replicon | chromosome |
| Accession | NZ_CP039704 | ||
| Organism | Hankyongella ginsenosidimutans strain W1-2-3 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | E6W36_RS10780 | Protein ID | WP_281277298.1 |
| Coordinates | 1840112..1840408 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | E6W36_RS10785 | Protein ID | WP_222872601.1 |
| Coordinates | 1840408..1840629 (-) | Length | 74 a.a. |
Genomic Context
Location: 1837695..1838165 (471 bp)
Type: Others
Protein ID: WP_222872600.1
Type: Others
Protein ID: WP_222872600.1
Location: 1840829..1841876 (1048 bp)
Type: Others
Protein ID: Protein_2291
Type: Others
Protein ID: Protein_2291
Location: 1841948..1842898 (951 bp)
Type: Others
Protein ID: WP_222872602.1
Type: Others
Protein ID: WP_222872602.1
Location: 1842935..1843486 (552 bp)
Type: Others
Protein ID: WP_222872603.1
Type: Others
Protein ID: WP_222872603.1
Location: 1843426..1845342 (1917 bp)
Type: Others
Protein ID: WP_222872604.1
Type: Others
Protein ID: WP_222872604.1
Location: 1835174..1835911 (738 bp)
Type: Others
Protein ID: WP_281277297.1
Type: Others
Protein ID: WP_281277297.1
Location: 1835869..1836894 (1026 bp)
Type: Others
Protein ID: WP_222872598.1
Type: Others
Protein ID: WP_222872598.1
Location: 1837051..1837524 (474 bp)
Type: Others
Protein ID: WP_222872599.1
Type: Others
Protein ID: WP_222872599.1
Location: 1838258..1840011 (1754 bp)
Type: Others
Protein ID: Protein_2288
Type: Others
Protein ID: Protein_2288
Location: 1840112..1840408 (297 bp)
Type: Toxin
Protein ID: WP_281277298.1
Type: Toxin
Protein ID: WP_281277298.1
Location: 1840408..1840629 (222 bp)
Type: Antitoxin
Protein ID: WP_222872601.1
Type: Antitoxin
Protein ID: WP_222872601.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E6W36_RS20720 (E6W36_10190) | 1835174..1835911 | - | 738 | WP_281277297.1 | calcium-binding protein | - |
| E6W36_RS10760 (E6W36_10195) | 1835869..1836894 | - | 1026 | WP_222872598.1 | M10 family metallopeptidase | - |
| E6W36_RS10765 (E6W36_10200) | 1837051..1837524 | - | 474 | WP_222872599.1 | Hsp20 family protein | - |
| E6W36_RS10770 (E6W36_10205) | 1837695..1838165 | + | 471 | WP_222872600.1 | DUF1465 family protein | - |
| E6W36_RS10775 (E6W36_10210) | 1838258..1840011 | - | 1754 | Protein_2288 | DNA mismatch repair endonuclease MutL | - |
| E6W36_RS10780 (E6W36_10215) | 1840112..1840408 | - | 297 | WP_281277298.1 | PIN domain-containing protein | Toxin |
| E6W36_RS10785 (E6W36_10220) | 1840408..1840629 | - | 222 | WP_222872601.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| E6W36_RS10790 (E6W36_10225) | 1840829..1841876 | + | 1048 | Protein_2291 | rod shape-determining protein | - |
| E6W36_RS10795 (E6W36_10230) | 1841948..1842898 | + | 951 | WP_222872602.1 | rod shape-determining protein MreC | - |
| E6W36_RS10800 (E6W36_10235) | 1842935..1843486 | + | 552 | WP_222872603.1 | rod shape-determining protein MreD | - |
| E6W36_RS10805 (E6W36_10240) | 1843426..1845342 | + | 1917 | WP_222872604.1 | penicillin-binding protein 2 | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10966.55 Da Isoelectric Point: 9.1936
>T124218 WP_281277298.1 NZ_CP039704:c1840408-1840112 [Hankyongella ginsenosidimutans]
MLRYMLDTDLCIRVLRDRPAPARERFNREARGLCISTVSLHELLYGAERSARPDHYRVEVARFAARLQVLAFDADAAAHA
ADIRATLEKAGRPSAATT
MLRYMLDTDLCIRVLRDRPAPARERFNREARGLCISTVSLHELLYGAERSARPDHYRVEVARFAARLQVLAFDADAAAHA
ADIRATLEKAGRPSAATT
Download Length: 297 bp
>T124218 NZ_CP039704:c1840408-1840112 [Hankyongella ginsenosidimutans]
ATGCTGCGTTACATGCTGGACACCGACCTATGCATCCGGGTGCTGCGCGACCGGCCGGCCCCGGCGCGCGAAAGGTTCAA
CCGGGAAGCACGGGGTCTGTGCATCTCGACCGTCAGTCTCCATGAACTGCTCTACGGTGCAGAGCGCTCGGCCCGCCCAG
ACCACTACCGTGTCGAAGTCGCGCGCTTTGCCGCGCGTTTGCAAGTGCTCGCTTTCGATGCCGACGCTGCCGCGCATGCG
GCGGACATTCGCGCCACGCTGGAAAAAGCGGGCAGGCCATCGGCAGCTACGACCTGA
ATGCTGCGTTACATGCTGGACACCGACCTATGCATCCGGGTGCTGCGCGACCGGCCGGCCCCGGCGCGCGAAAGGTTCAA
CCGGGAAGCACGGGGTCTGTGCATCTCGACCGTCAGTCTCCATGAACTGCTCTACGGTGCAGAGCGCTCGGCCCGCCCAG
ACCACTACCGTGTCGAAGTCGCGCGCTTTGCCGCGCGTTTGCAAGTGCTCGCTTTCGATGCCGACGCTGCCGCGCATGCG
GCGGACATTCGCGCCACGCTGGAAAAAGCGGGCAGGCCATCGGCAGCTACGACCTGA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8145.29 Da Isoelectric Point: 6.2389
>AT124218 WP_222872601.1 NZ_CP039704:c1840629-1840408 [Hankyongella ginsenosidimutans]
MTRTTLFQSNRTQAVRLPKAVAFPEGTNEVVILIDGNTRILIPSEALWDDFFAAEGIALGPRQKPATQQRETF
MTRTTLFQSNRTQAVRLPKAVAFPEGTNEVVILIDGNTRILIPSEALWDDFFAAEGIALGPRQKPATQQRETF
Download Length: 222 bp
>AT124218 NZ_CP039704:c1840629-1840408 [Hankyongella ginsenosidimutans]
ATGACACGCACGACCCTGTTTCAATCAAACCGGACCCAGGCTGTGCGGCTGCCCAAAGCGGTCGCATTTCCGGAGGGGAC
CAACGAAGTCGTGATTCTGATCGACGGCAACACGCGCATCCTCATCCCGTCGGAAGCCCTCTGGGACGATTTCTTCGCCG
CCGAAGGCATCGCGCTCGGGCCGCGCCAGAAACCGGCGACCCAGCAGCGCGAAACCTTCTGA
ATGACACGCACGACCCTGTTTCAATCAAACCGGACCCAGGCTGTGCGGCTGCCCAAAGCGGTCGCATTTCCGGAGGGGAC
CAACGAAGTCGTGATTCTGATCGACGGCAACACGCGCATCCTCATCCCGTCGGAAGCCCTCTGGGACGATTTCTTCGCCG
CCGAAGGCATCGCGCTCGGGCCGCGCCAGAAACCGGCGACCCAGCAGCGCGAAACCTTCTGA