Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1579506..1579897 Replicon chromosome
Accession NZ_CP039704
Organism Hankyongella ginsenosidimutans strain W1-2-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E6W36_RS09265 Protein ID WP_222872404.1
Coordinates 1579727..1579897 (+) Length 57 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E6W36_RS09260 Protein ID WP_222872403.1
Coordinates 1579506..1579739 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6W36_RS09240 (E6W36_08725) 1574630..1575838 - 1209 WP_222872400.1 RHS repeat-associated core domain-containing protein -
E6W36_RS09245 (E6W36_08730) 1576378..1577277 - 900 WP_246047464.1 RHS repeat-associated core domain-containing protein -
E6W36_RS09250 (E6W36_08735) 1577326..1578006 - 681 WP_222872402.1 phosphoglycolate phosphatase -
E6W36_RS09255 (E6W36_08740) 1578097..1579478 + 1382 Protein_1975 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
E6W36_RS09260 (E6W36_08745) 1579506..1579739 + 234 WP_222872403.1 ribbon-helix-helix protein, CopG family Antitoxin
E6W36_RS09265 (E6W36_08750) 1579727..1579897 + 171 WP_222872404.1 hypothetical protein Toxin
E6W36_RS09270 (E6W36_08755) 1580137..1580280 + 144 WP_222872405.1 hypothetical protein -
E6W36_RS09275 (E6W36_08760) 1580294..1581043 - 750 WP_222872406.1 hypothetical protein -
E6W36_RS09280 (E6W36_08765) 1581171..1582990 + 1820 Protein_1980 glutamine--fructose-6-phosphate transaminase (isomerizing) -
E6W36_RS09285 (E6W36_08770) 1583101..1583280 + 180 WP_222872407.1 hypothetical protein -
E6W36_RS09290 (E6W36_08775) 1583312..1583755 + 444 WP_222872408.1 hypothetical protein -
E6W36_RS09295 (E6W36_08780) 1583762..1584061 + 300 WP_222872409.1 Plug domain-containing protein -
E6W36_RS20630 (E6W36_08785) 1584058..1584348 + 291 WP_222872410.1 TonB-dependent receptor plug domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(21-44)


Sequences

Toxin        


Download         Length: 57 a.a.        Molecular weight: 6197.21 Da        Isoelectric Point: 4.2195

>T124216 WP_222872404.1 NZ_CP039704:1579727-1579897 [Hankyongella ginsenosidimutans]
MAGLIFDTNILIDFLRGIELARVLIDTTPDRAISMISWMEVLCGAGPDRDAATRNF

Download         Length: 171 bp

>T124216 NZ_CP039704:1579727-1579897 [Hankyongella ginsenosidimutans]
ATGGCCGGACTGATCTTCGACACCAACATTCTGATCGATTTCCTGCGCGGGATAGAACTGGCTCGTGTCCTGATCGACAC
AACGCCTGACCGCGCCATCAGCATGATAAGCTGGATGGAAGTGCTCTGCGGCGCTGGCCCGGACCGAGACGCCGCAACCC
GCAACTTTTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8885.07 Da        Isoelectric Point: 11.0396

>AT124216 WP_222872403.1 NZ_CP039704:1579506-1579739 [Hankyongella ginsenosidimutans]
MISFPLRTLVDIPRADLGSRDRLARHRKESRAALIRAAVRQYLADNSADRLREAFGLWRDGEDGLAHQARMRAEWPD

Download         Length: 234 bp

>AT124216 NZ_CP039704:1579506-1579739 [Hankyongella ginsenosidimutans]
ATGATATCGTTTCCGCTGCGGACACTTGTAGACATTCCACGCGCCGATCTAGGATCGCGGGATCGTCTGGCCAGGCATCG
CAAGGAGTCGCGTGCCGCCCTGATCCGCGCAGCAGTGCGGCAGTATCTGGCGGATAACAGCGCAGACCGCTTGCGTGAGG
CCTTCGGCCTGTGGCGCGACGGCGAAGACGGTCTGGCGCATCAGGCCAGAATGCGCGCCGAATGGCCGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References