Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 1296342..1296852 Replicon chromosome
Accession NZ_CP039704
Organism Hankyongella ginsenosidimutans strain W1-2-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E6W36_RS07560 Protein ID WP_222874238.1
Coordinates 1296673..1296852 (+) Length 60 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E6W36_RS07555 Protein ID WP_222874237.1
Coordinates 1296342..1296530 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6W36_RS07520 (E6W36_07085) 1291783..1292154 - 372 WP_222874232.1 hypothetical protein -
E6W36_RS07525 (E6W36_07090) 1292632..1292904 + 273 WP_222874233.1 hypothetical protein -
E6W36_RS07530 (E6W36_07095) 1293189..1293770 + 582 WP_222874234.1 phage minor head protein -
E6W36_RS07535 (E6W36_07100) 1293845..1294357 + 513 WP_222874235.1 hypothetical protein -
E6W36_RS07540 (E6W36_07110) 1294847..1295200 + 354 WP_246048227.1 hypothetical protein -
E6W36_RS18460 1295356..1295559 + 204 WP_246048228.1 hypothetical protein -
E6W36_RS18465 (E6W36_07115) 1295511..1296166 + 656 Protein_1631 nitrilase-related carbon-nitrogen hydrolase -
E6W36_RS07555 (E6W36_07120) 1296342..1296530 + 189 WP_222874237.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
E6W36_RS07560 1296673..1296852 + 180 WP_222874238.1 hypothetical protein Toxin
E6W36_RS20575 (E6W36_07130) 1297025..1297774 + 750 Protein_1634 TlyA family RNA methyltransferase -
E6W36_RS07570 (E6W36_07135) 1297968..1299191 + 1224 WP_222874239.1 class I SAM-dependent RNA methyltransferase -
E6W36_RS18480 1299196..1299834 - 639 WP_246048229.1 amidohydrolase family protein -
E6W36_RS18485 1299744..1300247 - 504 WP_246048230.1 amidohydrolase family protein -
E6W36_RS18490 1300232..1300462 - 231 WP_246048231.1 hypothetical protein -
E6W36_RS07580 (E6W36_07145) 1300672..1301006 - 335 Protein_1639 iron-sulfur cluster assembly accessory protein -
E6W36_RS07585 (E6W36_07150) 1301009..1301308 - 300 Protein_1640 SUF system Fe-S cluster assembly protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6334.40 Da        Isoelectric Point: 4.7922

>T124215 WP_222874238.1 NZ_CP039704:1296673-1296852 [Hankyongella ginsenosidimutans]
VLGLLDALPQAPIADAMELQQMIERRAVYGRGIGYVDAHLLASTLLEGGLRLLTKSLSD

Download         Length: 180 bp

>T124215 NZ_CP039704:1296673-1296852 [Hankyongella ginsenosidimutans]
GTGCTTGGCCTGCTGGACGCCTTGCCGCAGGCACCGATCGCCGATGCGATGGAACTGCAGCAGATGATCGAGCGGCGCGC
GGTCTATGGGCGCGGGATCGGTTATGTCGATGCCCATCTGCTGGCGTCCACGCTGCTCGAGGGTGGGCTGCGGCTGCTGA
CCAAGAGCCTTTCCGACTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6777.87 Da        Isoelectric Point: 9.5196

>AT124215 WP_222874237.1 NZ_CP039704:1296342-1296530 [Hankyongella ginsenosidimutans]
MRTTVTLDDERLARAMALSGEVERSVLLHRALDALIALESARRLALLAGSEPALEAAPRRRP

Download         Length: 189 bp

>AT124215 NZ_CP039704:1296342-1296530 [Hankyongella ginsenosidimutans]
ATGCGGACGACCGTTACTCTGGATGACGAACGGCTGGCGCGCGCTATGGCGCTCTCCGGCGAAGTGGAGCGCAGCGTACT
GCTGCACCGGGCGCTTGATGCGTTGATTGCCCTGGAAAGCGCGCGCCGGCTGGCGCTGCTGGCTGGATCAGAGCCTGCGC
TCGAGGCCGCGCCCCGCCGCCGCCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References