Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2142373..2142932 Replicon chromosome
Accession NZ_CP039695
Organism Novosphingobium sp. ABRDHK2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FA702_RS10610 Protein ID WP_136956121.1
Coordinates 2142639..2142932 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FA702_RS10605 Protein ID WP_168196115.1
Coordinates 2142373..2142642 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FA702_RS10585 2137969..2138493 - 525 WP_136956118.1 hypothetical protein -
FA702_RS10590 2138625..2138819 - 195 WP_136956119.1 hypothetical protein -
FA702_RS10595 2138955..2141108 - 2154 WP_136956120.1 ParB/RepB/Spo0J family partition protein -
FA702_RS10600 2141224..2142072 - 849 WP_136957357.1 hypothetical protein -
FA702_RS10605 2142373..2142642 + 270 WP_168196115.1 ribbon-helix-helix domain-containing protein Antitoxin
FA702_RS10610 2142639..2142932 + 294 WP_136956121.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FA702_RS10620 2143312..2145009 + 1698 Protein_2101 recombinase family protein -
FA702_RS10630 2145175..2145585 + 411 WP_136956123.1 hypothetical protein -
FA702_RS10635 2145634..2146146 + 513 WP_136956124.1 MmcB family DNA repair protein -
FA702_RS10640 2146195..2146764 - 570 WP_136957359.1 TMEM165/GDT1 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(11-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11458.10 Da        Isoelectric Point: 7.2779

>T124206 WP_136956121.1 NZ_CP039695:2142639-2142932 [Novosphingobium sp. ABRDHK2]
MRIKWTGKASSDLVRLHEHLRPVAPEAAARVVQQLARAPDRLLDYPRIGEKLDAYEPREVRRIIVGNYELRYEIADATIF
ILRLWHCREERSFESDD

Download         Length: 294 bp

>T124206 NZ_CP039695:2142639-2142932 [Novosphingobium sp. ABRDHK2]
ATGAGGATCAAGTGGACCGGCAAGGCGTCCTCGGATCTGGTCCGGCTGCACGAGCATCTGCGCCCGGTCGCTCCGGAGGC
GGCGGCGCGGGTCGTACAGCAGCTCGCGCGCGCACCGGATCGGCTGCTCGACTATCCCCGGATCGGCGAGAAGCTGGACG
CCTACGAACCGCGCGAAGTCCGGCGCATCATCGTAGGCAACTACGAGCTGCGTTACGAGATAGCGGACGCGACAATCTTC
ATCCTGCGCCTGTGGCATTGCCGCGAGGAGCGCAGCTTCGAGTCGGACGATTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9894.26 Da        Isoelectric Point: 5.1057

>AT124206 WP_168196115.1 NZ_CP039695:2142373-2142642 [Novosphingobium sp. ABRDHK2]
MAIETKVLTTHVPLHLAEKVEAMASRLERSRGWVMKQALAAWVDQEEERHRMTLEALDDVDAGRVIDHQAVRAWADSLGT
DAPLPPPSA

Download         Length: 270 bp

>AT124206 NZ_CP039695:2142373-2142642 [Novosphingobium sp. ABRDHK2]
ATGGCGATCGAGACAAAAGTATTGACTACGCACGTCCCGCTGCATCTCGCGGAAAAGGTGGAAGCGATGGCCTCCCGGCT
TGAACGCTCGCGCGGCTGGGTGATGAAGCAAGCGCTCGCCGCCTGGGTAGATCAGGAGGAAGAGCGTCACCGGATGACGC
TCGAAGCGCTGGATGATGTCGATGCCGGGCGCGTGATCGACCATCAGGCCGTGCGCGCATGGGCGGACAGCCTCGGCACC
GACGCCCCGCTGCCGCCGCCTTCGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References