Detailed information of TA system TA124205

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 1484398..1484999
• Replicon: chromosome
• Accession: NZ_CP039695
• Organism: Novosphingobium sp. ABRDHK2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FA702_RS07310
• Protein ID: WP_136955596.1
• Coordinates: 1484751..1484999 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FA702_RS07305
• Protein ID: WP_210417602.1
• Coordinates: 1484398..1484754 (-)
• Length: 119 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FA702_RS07260	1479485..1480438	+	954	WP_136955587.1	hypothetical protein	-
FA702_RS22755	1480538..1481299	+	762	WP_168195954.1	hypothetical protein	-
FA702_RS07270	1481307..1481648	+	342	WP_136955589.1	hypothetical protein	-
FA702_RS07275	1481675..1481965	+	291	WP_136955590.1	hypothetical protein	-
FA702_RS07280	1481949..1482473	-	525	WP_136955591.1	zinc ribbon domain-containing protein	-
FA702_RS07285	1482705..1483169	-	465	WP_136955592.1	hypothetical protein	-
FA702_RS07290	1483166..1483744	-	579	WP_136955593.1	hypothetical protein	-
FA702_RS07295	1483744..1484112	-	369	WP_136955594.1	hypothetical protein	-
FA702_RS07300	1484206..1484382	+	177	WP_136955595.1	ribbon-helix-helix protein, CopG family	-
FA702_RS07305	1484398..1484754	-	357	WP_210417602.1	helix-turn-helix domain-containing protein	Antitoxin
FA702_RS07310	1484751..1484999	-	249	WP_136955596.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FA702_RS07315	1485159..1485470	+	312	WP_136955597.1	hypothetical protein	-
FA702_RS07320	1485544..1486824	+	1281	WP_136955598.1	hypothetical protein	-
FA702_RS07325	1487598..1488038	-	441	WP_136955599.1	hypothetical protein	-
FA702_RS07330	1488035..1488247	-	213	WP_136955600.1	hypothetical protein	-
FA702_RS07335	1488247..1488456	-	210	WP_136955601.1	hypothetical protein	-
FA702_RS07340	1488453..1488692	-	240	WP_136955602.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1473525..1499928	26403

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (63-117)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 9007.58 Da
• Isoelectric Point: 10.4509

>T124205 WP_136955596.1 NZ_CP039695:c1484999-1484751 [Novosphingobium sp. ABRDHK2]
MKPISYTRAAIKTLRKMPANDAARIISKVEQYAADPVSLANNVKALKGREGIRLRVGDWRVIMDDGVVLAVLEIGPRGGI
YE

Nucleotide

• Length: 249 bp

>T124205 NZ_CP039695:c1484999-1484751 [Novosphingobium sp. ABRDHK2]
ATGAAGCCGATCAGCTATACCCGCGCCGCGATCAAGACCCTTCGCAAGATGCCCGCGAATGATGCTGCTCGGATCATCAG
CAAGGTCGAGCAATATGCGGCTGATCCGGTATCGCTCGCGAACAACGTCAAGGCGCTCAAGGGTCGCGAAGGGATCAGGC
TGCGGGTCGGCGACTGGCGCGTCATCATGGATGATGGCGTGGTGTTGGCCGTTCTGGAAATTGGGCCGCGCGGCGGCATC
TACGAATGA

Antitoxin

Protein

• Length: 119 a.a.
• Molecular weight: 12925.86 Da
• Isoelectric Point: 4.5984

>AT124205 WP_210417602.1 NZ_CP039695:c1484754-1484398 [Novosphingobium sp. ABRDHK2]
MMEMNMGEMITIPLDEYRNLKAAVDELADLRTYDRAMTDIAAGRDELVPADVAKRLVSGENPLRVWREFRGMTQATLSSA
SGVNRVQIADIEAGRKKGSVETVCKLAAALQVGVEDLV

Nucleotide

• Length: 357 bp

>AT124205 NZ_CP039695:c1484754-1484398 [Novosphingobium sp. ABRDHK2]
ATGATGGAGATGAACATGGGCGAGATGATTACGATCCCGCTGGACGAGTACCGGAACCTCAAGGCTGCGGTCGATGAACT
CGCCGATCTGCGCACCTATGATCGCGCCATGACCGACATCGCCGCCGGCCGCGATGAGCTGGTGCCAGCCGATGTTGCGA
AGCGGCTTGTTAGCGGGGAAAACCCCTTGCGCGTCTGGCGTGAGTTTCGCGGCATGACACAAGCCACCCTGTCCAGCGCG
TCGGGCGTGAACCGCGTTCAGATTGCTGACATCGAAGCCGGCCGGAAGAAAGGTTCGGTAGAGACTGTGTGCAAGCTGGC
GGCGGCGCTGCAGGTTGGTGTTGAGGACTTGGTTTAG