Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1339363..1340845 Replicon chromosome
Accession NZ_CP039695
Organism Novosphingobium sp. ABRDHK2

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag FA702_RS06495 Protein ID WP_136955458.1
Coordinates 1339363..1340232 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag FA702_RS06500 Protein ID WP_136955459.1
Coordinates 1340225..1340845 (-) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FA702_RS06465 1334868..1335020 + 153 WP_136957285.1 helix-turn-helix domain-containing protein -
FA702_RS06470 1335352..1335624 + 273 Protein_1276 DUF4102 domain-containing protein -
FA702_RS06480 1336901..1337440 + 540 Protein_1278 hypothetical protein -
FA702_RS06485 1337574..1338569 + 996 WP_168196008.1 DUF4238 domain-containing protein -
FA702_RS06490 1338571..1339023 - 453 WP_136955457.1 hypothetical protein -
FA702_RS06495 1339363..1340232 - 870 WP_136955458.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FA702_RS06500 1340225..1340845 - 621 WP_136955459.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
FA702_RS06505 1341280..1342059 - 780 WP_006955904.1 IS21-like element ISRsp3 family helper ATPase IstB -
FA702_RS06510 1342072..1343001 - 930 WP_136955460.1 DUF935 family protein -
FA702_RS06515 1343004..1343396 - 393 WP_136955461.1 hypothetical protein -
FA702_RS06520 1343396..1344868 - 1473 WP_136955462.1 terminase family protein -
FA702_RS06525 1344868..1345407 - 540 WP_136955463.1 DUF3486 family protein -
FA702_RS06530 1345409..1345699 - 291 WP_136955464.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1306847..1372291 65444
- flank IS/Tn - - 1341280..1342059 779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(23-55)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32167.89 Da        Isoelectric Point: 4.8826

>T124204 WP_136955458.1 NZ_CP039695:c1340232-1339363 [Novosphingobium sp. ABRDHK2]
MARSPVNLAKSVKDRLLNISRREGRAFDVLLVRFALERLLYRLSVSEYRERFVLKGGMLVTAWIDDDNRVTLDADFLGHG
DANPDKLVADFRAIMQIEGGDGLVFDAEGLVATAIREEMEYGGVRLKTAAYLERTRIPVTIDIGFGDALADAAQQLDYPT
LLDLPVPHIRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRNLEIASEDLDVAIRATFERRGTPIPTERPPGLSA
KMMEDETKQRQWRAYAASVELEGVGLNSIIDAVWNLVGPSCERLSAKTA

Download         Length: 870 bp

>T124204 NZ_CP039695:c1340232-1339363 [Novosphingobium sp. ABRDHK2]
ATGGCTAGATCGCCCGTCAATCTCGCCAAGTCGGTCAAGGATCGCCTGCTCAATATTTCGCGAAGAGAAGGCCGCGCGTT
CGACGTTCTGCTGGTCCGCTTCGCGCTTGAGCGCCTCCTCTATCGGCTGTCGGTCTCGGAATATCGCGAGCGATTCGTGC
TCAAGGGCGGAATGCTGGTCACGGCGTGGATCGACGACGACAATCGAGTCACGCTAGATGCCGACTTCCTGGGCCATGGC
GACGCCAATCCCGACAAGCTGGTCGCCGACTTCCGGGCAATCATGCAAATTGAAGGAGGCGACGGCCTTGTGTTCGACGC
CGAAGGATTGGTTGCCACAGCGATCCGCGAGGAAATGGAATACGGCGGCGTCAGGCTCAAGACGGCGGCCTATCTCGAGC
GCACGCGAATACCGGTGACAATCGACATCGGCTTCGGCGATGCGCTGGCGGATGCCGCTCAACAACTCGACTACCCGACG
CTGCTCGATCTCCCTGTCCCGCACATTAGGTCCTACCCGCCGGCGACGGTCATTGCCGAGAAGTTCCAGGCGATGGTGGC
GCTCGGCGTGCTCAATGGCCGGATGAAGGACTATTATGACCTATGGGCCATACCCAGGAATCTGGAGATCGCCTCCGAGG
ATCTGGATGTGGCCATCCGCGCGACTTTCGAGCGGCGCGGAACACCTATCCCGACAGAACGGCCGCCCGGGCTTTCAGCC
AAGATGATGGAGGACGAAACGAAACAGCGCCAATGGCGTGCTTATGCCGCTTCCGTCGAACTCGAAGGCGTTGGTCTGAA
TTCCATCATTGATGCGGTGTGGAATCTTGTGGGCCCCTCATGCGAAAGGCTGTCGGCAAAGACTGCCTAA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 22721.11 Da        Isoelectric Point: 10.7851

>AT124204 WP_136955459.1 NZ_CP039695:c1340845-1340225 [Novosphingobium sp. ABRDHK2]
MASRPISQRTKLRSLFTAHTMRRAGELRAAGIGPQTIARAVEEGELERISRGLYQRRDSEIEEHQILAEAAIRVPKGVIA
LTSALAFHGLTDQMPRRIWMAIGTSDWSPVQSYPPLRIVRFTDSYLRQGVEHHTIAGVNVPIYSIPKTLADAFRNPKLVD
RSVAVEGLRAAIEQRKTTPSAIAEGAKAGGAWKTMRPYLEALTANG

Download         Length: 621 bp

>AT124204 NZ_CP039695:c1340845-1340225 [Novosphingobium sp. ABRDHK2]
ATGGCCTCGAGGCCCATCTCGCAACGGACAAAGCTTCGCAGTCTATTTACCGCCCATACAATGAGGCGCGCGGGAGAGCT
GCGTGCCGCCGGTATCGGTCCGCAAACGATAGCGCGGGCCGTCGAGGAAGGTGAACTCGAGCGCATCTCGCGTGGCCTGT
ATCAGCGGCGCGACTCAGAGATTGAGGAGCACCAAATACTGGCTGAAGCTGCGATCCGGGTTCCCAAGGGCGTCATTGCC
CTGACCTCGGCCCTGGCCTTTCACGGCCTGACTGATCAAATGCCGAGACGGATATGGATGGCGATCGGCACGAGCGATTG
GTCGCCAGTGCAATCCTATCCGCCACTTCGGATCGTACGCTTCACCGACTCCTATCTTCGCCAAGGCGTCGAGCATCATA
CGATCGCCGGCGTAAACGTACCTATCTATTCGATTCCGAAGACCCTCGCCGATGCGTTCCGCAATCCCAAGCTGGTCGAT
CGTTCGGTCGCAGTCGAAGGACTTCGTGCGGCAATCGAGCAACGCAAGACGACACCGAGCGCAATCGCCGAAGGAGCCAA
GGCCGGCGGTGCCTGGAAGACCATGCGCCCTTATCTCGAGGCCCTCACCGCCAATGGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References