Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pasABC/RelE-HTH |
Location | 2554085..2554571 | Replicon | chromosome |
Accession | NZ_CP039691 | ||
Organism | Agrobacterium larrymoorei strain CFBP5473 |
Toxin (Protein)
Gene name | pasB | Uniprot ID | A0A4D7DPW2 |
Locus tag | CFBP5473_RS12430 | Protein ID | WP_027673882.1 |
Coordinates | 2554302..2554571 (+) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | pasA | Uniprot ID | A0A4D7E236 |
Locus tag | CFBP5473_RS12425 | Protein ID | WP_027673883.1 |
Coordinates | 2554085..2554318 (+) | Length | 78 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CFBP5473_RS12400 | 2549409..2549855 | + | 447 | WP_027673887.1 | DoxX family protein | - |
CFBP5473_RS12405 | 2549907..2550317 | - | 411 | WP_027673886.1 | GFA family protein | - |
CFBP5473_RS12410 | 2550463..2551161 | - | 699 | WP_027673885.1 | ATP phosphoribosyltransferase | - |
CFBP5473_RS12415 | 2551158..2552279 | - | 1122 | WP_027673884.1 | ATP phosphoribosyltransferase regulatory subunit | - |
CFBP5473_RS12420 | 2552288..2553931 | - | 1644 | WP_051441151.1 | histidine--tRNA ligase | - |
CFBP5473_RS12425 | 2554085..2554318 | + | 234 | WP_027673883.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
CFBP5473_RS12430 | 2554302..2554571 | + | 270 | WP_027673882.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CFBP5473_RS12435 | 2554575..2555339 | + | 765 | WP_027673881.1 | hypothetical protein | - |
CFBP5473_RS25075 | 2555582..2555740 | + | 159 | WP_157835785.1 | hypothetical protein | - |
CFBP5473_RS12440 | 2555792..2556157 | + | 366 | WP_027673879.1 | DUF305 domain-containing protein | - |
CFBP5473_RS12445 | 2556206..2557120 | - | 915 | WP_027673878.1 | LysR family transcriptional regulator | - |
CFBP5473_RS12450 | 2557202..2558239 | + | 1038 | WP_027673877.1 | putative sulfate exporter family transporter | - |
CFBP5473_RS12455 | 2558236..2558658 | - | 423 | WP_027673876.1 | hypothetical protein | - |
CFBP5473_RS12460 | 2558676..2559305 | - | 630 | WP_027673875.1 | DNA-3-methyladenine glycosylase I | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10564.19 Da Isoelectric Point: 10.5156
>T124201 WP_027673882.1 NZ_CP039691:2554302-2554571 [Agrobacterium larrymoorei]
MIWEIEFRESARKQLKKLGRQDATRIIAFLSDRISADTNPRRTGQALQGSELGKFWRYRVGDYRIICDIQDQKLVIIAIE
IGHRREVYR
MIWEIEFRESARKQLKKLGRQDATRIIAFLSDRISADTNPRRTGQALQGSELGKFWRYRVGDYRIICDIQDQKLVIIAIE
IGHRREVYR
Download Length: 270 bp
>T124201 NZ_CP039691:2554302-2554571 [Agrobacterium larrymoorei]
TTGATCTGGGAAATTGAATTTCGAGAGTCTGCGCGCAAGCAATTGAAGAAGCTTGGCAGACAGGACGCAACGCGGATCAT
TGCATTTTTGAGTGATCGGATTTCCGCAGACACAAATCCAAGACGAACCGGTCAGGCACTTCAAGGCTCAGAGCTCGGCA
AATTCTGGCGTTATCGCGTCGGTGACTATCGTATTATATGCGACATTCAGGATCAAAAACTTGTCATTATCGCCATCGAA
ATCGGCCACCGCCGGGAAGTATATCGTTAA
TTGATCTGGGAAATTGAATTTCGAGAGTCTGCGCGCAAGCAATTGAAGAAGCTTGGCAGACAGGACGCAACGCGGATCAT
TGCATTTTTGAGTGATCGGATTTCCGCAGACACAAATCCAAGACGAACCGGTCAGGCACTTCAAGGCTCAGAGCTCGGCA
AATTCTGGCGTTATCGCGTCGGTGACTATCGTATTATATGCGACATTCAGGATCAAAAACTTGTCATTATCGCCATCGAA
ATCGGCCACCGCCGGGAAGTATATCGTTAA
Antitoxin
Download Length: 78 a.a. Molecular weight: 9034.08 Da Isoelectric Point: 4.7119
>AT124201 WP_027673883.1 NZ_CP039691:2554085-2554318 [Agrobacterium larrymoorei]
MSKQTAIRLPDDTYERLKALSERTGRTSAFYIREAIEKHIEDMEDLYLAEEATRRHIANGERTYSLEEVMRDIDLGN
MSKQTAIRLPDDTYERLKALSERTGRTSAFYIREAIEKHIEDMEDLYLAEEATRRHIANGERTYSLEEVMRDIDLGN
Download Length: 234 bp
>AT124201 NZ_CP039691:2554085-2554318 [Agrobacterium larrymoorei]
ATGAGCAAACAAACCGCAATCCGTCTGCCGGATGATACCTATGAGCGGCTGAAGGCGCTTTCAGAGCGCACGGGCCGCAC
CTCCGCCTTTTATATCCGAGAAGCCATCGAAAAGCACATCGAGGATATGGAGGATTTGTATCTGGCGGAAGAAGCGACGC
GGCGACACATTGCAAATGGTGAGCGCACCTATAGTCTTGAAGAAGTGATGCGCGATATTGATCTGGGAAATTGA
ATGAGCAAACAAACCGCAATCCGTCTGCCGGATGATACCTATGAGCGGCTGAAGGCGCTTTCAGAGCGCACGGGCCGCAC
CTCCGCCTTTTATATCCGAGAAGCCATCGAAAAGCACATCGAGGATATGGAGGATTTGTATCTGGCGGAAGAAGCGACGC
GGCGACACATTGCAAATGGTGAGCGCACCTATAGTCTTGAAGAAGTGATGCGCGATATTGATCTGGGAAATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7DPW2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7E236 |