Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/ParE-RHH |
Location | 2341077..2341615 | Replicon | chromosome |
Accession | NZ_CP039691 | ||
Organism | Agrobacterium larrymoorei strain CFBP5473 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A4D7DQ75 |
Locus tag | CFBP5473_RS11385 | Protein ID | WP_027675635.1 |
Coordinates | 2341322..2341615 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A4D7DS04 |
Locus tag | CFBP5473_RS11380 | Protein ID | WP_027675634.1 |
Coordinates | 2341077..2341325 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CFBP5473_RS11340 | 2336662..2337150 | - | 489 | WP_027675627.1 | DUF1579 domain-containing protein | - |
CFBP5473_RS11345 | 2337164..2337892 | - | 729 | WP_027675628.1 | thioredoxin family protein | - |
CFBP5473_RS11350 | 2338013..2338459 | + | 447 | WP_027675629.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
CFBP5473_RS11360 | 2338602..2339366 | - | 765 | WP_027675630.1 | RES family NAD+ phosphorylase | - |
CFBP5473_RS11365 | 2339326..2339709 | - | 384 | WP_027675631.1 | MbcA/ParS/Xre antitoxin family protein | - |
CFBP5473_RS11370 | 2339833..2340258 | - | 426 | WP_027675632.1 | organic hydroperoxide resistance protein | - |
CFBP5473_RS11375 | 2340453..2340914 | + | 462 | WP_027675633.1 | MarR family transcriptional regulator | - |
CFBP5473_RS11380 | 2341077..2341325 | + | 249 | WP_027675634.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
CFBP5473_RS11385 | 2341322..2341615 | + | 294 | WP_027675635.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CFBP5473_RS11390 | 2341669..2342007 | - | 339 | WP_051441286.1 | NINE protein | - |
CFBP5473_RS11395 | 2342139..2342873 | - | 735 | WP_027675637.1 | L,D-transpeptidase | - |
CFBP5473_RS11400 | 2343074..2343958 | - | 885 | WP_027675638.1 | L,D-transpeptidase | - |
CFBP5473_RS11405 | 2344072..2345013 | - | 942 | WP_027675639.1 | S9 family peptidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11088.47 Da Isoelectric Point: 6.3222
>T124200 WP_027675635.1 NZ_CP039691:2341322-2341615 [Agrobacterium larrymoorei]
MKALALSPAAEADLDHIWEHSATNWGLDQADRYTDEIRDACLDLAAGVRHGRPVDVRSGYLKYNTGAHMIYFRDQGDRLD
IVRILHQRQDVIFNLPK
MKALALSPAAEADLDHIWEHSATNWGLDQADRYTDEIRDACLDLAAGVRHGRPVDVRSGYLKYNTGAHMIYFRDQGDRLD
IVRILHQRQDVIFNLPK
Download Length: 294 bp
>T124200 NZ_CP039691:2341322-2341615 [Agrobacterium larrymoorei]
ATGAAGGCCCTTGCTCTCTCGCCTGCGGCAGAAGCGGACCTTGACCACATTTGGGAACACAGCGCCACGAATTGGGGGCT
GGATCAGGCCGACCGCTATACCGATGAAATCCGGGATGCCTGCCTTGATCTGGCCGCTGGCGTCAGGCATGGCCGCCCGG
TCGATGTACGCTCCGGCTATCTGAAATATAACACCGGCGCGCATATGATCTACTTCCGCGATCAAGGTGACAGGCTGGAT
ATCGTTCGCATTTTGCATCAAAGACAGGACGTAATCTTTAACCTGCCCAAGTAG
ATGAAGGCCCTTGCTCTCTCGCCTGCGGCAGAAGCGGACCTTGACCACATTTGGGAACACAGCGCCACGAATTGGGGGCT
GGATCAGGCCGACCGCTATACCGATGAAATCCGGGATGCCTGCCTTGATCTGGCCGCTGGCGTCAGGCATGGCCGCCCGG
TCGATGTACGCTCCGGCTATCTGAAATATAACACCGGCGCGCATATGATCTACTTCCGCGATCAAGGTGACAGGCTGGAT
ATCGTTCGCATTTTGCATCAAAGACAGGACGTAATCTTTAACCTGCCCAAGTAG
Antitoxin
Download Length: 83 a.a. Molecular weight: 9218.25 Da Isoelectric Point: 7.2036
>AT124200 WP_027675634.1 NZ_CP039691:2341077-2341325 [Agrobacterium larrymoorei]
MARNTSITLGDHFASFIRDQVQTGRYGSTSDVVRAGLRLLEEHEAKVKSLQDALIAGEQSGEPRAFDFEAFKTRKRAEYE
GR
MARNTSITLGDHFASFIRDQVQTGRYGSTSDVVRAGLRLLEEHEAKVKSLQDALIAGEQSGEPRAFDFEAFKTRKRAEYE
GR
Download Length: 249 bp
>AT124200 NZ_CP039691:2341077-2341325 [Agrobacterium larrymoorei]
ATGGCCCGGAACACCTCTATAACGCTCGGAGATCACTTCGCCAGCTTTATCAGGGACCAGGTGCAGACAGGTCGCTACGG
CTCTACGAGTGACGTTGTCCGAGCAGGACTGCGGCTGCTGGAAGAGCATGAGGCCAAGGTGAAGTCCCTTCAAGACGCCC
TGATCGCCGGGGAGCAGTCAGGGGAGCCACGAGCTTTCGACTTTGAGGCATTCAAGACTCGCAAGCGCGCAGAGTATGAG
GGCCGATGA
ATGGCCCGGAACACCTCTATAACGCTCGGAGATCACTTCGCCAGCTTTATCAGGGACCAGGTGCAGACAGGTCGCTACGG
CTCTACGAGTGACGTTGTCCGAGCAGGACTGCGGCTGCTGGAAGAGCATGAGGCCAAGGTGAAGTCCCTTCAAGACGCCC
TGATCGCCGGGGAGCAGTCAGGGGAGCCACGAGCTTTCGACTTTGAGGCATTCAAGACTCGCAAGCGCGCAGAGTATGAG
GGCCGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7DQ75 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7DS04 |