Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 997949..998514 Replicon chromosome
Accession NZ_CP039691
Organism Agrobacterium larrymoorei strain CFBP5473

Toxin (Protein)


Gene name parE Uniprot ID A0A4D7DZI7
Locus tag CFBP5473_RS04705 Protein ID WP_027674231.1
Coordinates 998221..998514 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4D7DSM4
Locus tag CFBP5473_RS04700 Protein ID WP_027674230.1
Coordinates 997949..998233 (+) Length 95 a.a.

Genomic Context

CFBP5473_RS04670CFBP5473_RS04675CFBP5473_RS04695CFBP5473_RS04700CFBP5473_RS04705CFBP5473_RS04720CFBP5473_RS04680CFBP5473_RS04685CFBP5473_RS04690CFBP5473_RS04710CFBP5473_RS04715
Location: 993665..994312 (648 bp)
Type: Others
Protein ID: WP_027674224.1
Location: 994309..995556 (1248 bp)
Type: Others
Protein ID: WP_027674225.1
Location: 997596..997871 (276 bp)
Type: Others
Protein ID: WP_027674229.1
Location: 997949..998233 (285 bp)
Type: Antitoxin
Protein ID: WP_027674230.1
Location: 998221..998514 (294 bp)
Type: Toxin
Protein ID: WP_027674231.1
Location: 1001300..1003156 (1857 bp)
Type: Others
Protein ID: WP_027674234.1
Location: 995786..995974 (189 bp)
Type: Others
Protein ID: WP_027674226.1
Location: 996126..996392 (267 bp)
Type: Others
Protein ID: WP_027674227.1
Location: 996559..997470 (912 bp)
Type: Others
Protein ID: WP_027674228.1
Location: 998540..1000192 (1653 bp)
Type: Others
Protein ID: WP_027674232.1
Location: 1000424..1000885 (462 bp)
Type: Others
Protein ID: WP_027674233.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFBP5473_RS04670993665..994312+648WP_027674224.1CoA pyrophosphatase-
CFBP5473_RS04675994309..995556+1248WP_027674225.1CCA tRNA nucleotidyltransferase-
CFBP5473_RS04680995786..995974-189WP_027674226.1DUF1059 domain-containing protein-
CFBP5473_RS04685996126..996392-267WP_027674227.1hypothetical protein-
CFBP5473_RS04690996559..997470-912WP_027674228.1oxygen-dependent coproporphyrinogen oxidase-
CFBP5473_RS04695997596..997871+276WP_027674229.1hypothetical protein-
CFBP5473_RS04700997949..998233+285WP_027674230.1ribbon-helix-helix protein, CopG familyAntitoxin
CFBP5473_RS04705998221..998514+294WP_027674231.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CFBP5473_RS04710998540..1000192-1653WP_027674232.1Na/Pi cotransporter family protein-
CFBP5473_RS047151000424..1000885-462WP_027674233.1tRNA (cytidine(34)-2'-O)-methyltransferase-
CFBP5473_RS047201001300..1003156+1857WP_027674234.1ABC transporter ATP-binding protein/permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11037.89 Da        Isoelectric Point: 9.5450

>T124196 WP_027674231.1 NZ_CP039691:998221-998514 [Agrobacterium larrymoorei]
MPQLIWTPEALRDVQRCYRFLAPKNPDAASRAIKSIREKMRMIVTHPAIGRPVDKMAPEFRELLIPFGESGYVALYRLDG
DLAVVLAVRHQNEAGYT

Download         Length: 294 bp

>T124196 NZ_CP039691:998221-998514 [Agrobacterium larrymoorei]
ATGCCACAACTGATCTGGACGCCAGAAGCACTCAGGGACGTTCAGCGCTGTTATCGTTTTCTTGCCCCGAAAAATCCAGA
TGCTGCATCTCGGGCGATAAAGTCCATTCGCGAAAAGATGCGGATGATCGTGACGCATCCGGCCATTGGCCGCCCCGTCG
ACAAGATGGCCCCGGAATTTCGGGAATTGCTTATTCCGTTTGGTGAGAGCGGCTATGTCGCGCTTTACCGTTTGGATGGT
GATCTGGCCGTGGTTTTGGCCGTGCGTCATCAAAATGAAGCTGGTTACACCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10729.96 Da        Isoelectric Point: 6.2152

>AT124196 WP_027674230.1 NZ_CP039691:997949-998233 [Agrobacterium larrymoorei]
MPGPHPVAVKLDPEVHARMRKLAQAQHRSTHYLMREAIAQYVEREEKRAAFRQDALEAWSAYQASGSHLNQTEADEWLAK
LEAGQDVEPPECHN

Download         Length: 285 bp

>AT124196 NZ_CP039691:997949-998233 [Agrobacterium larrymoorei]
ATGCCGGGACCACATCCAGTTGCGGTGAAGCTCGATCCGGAGGTCCACGCCCGGATGCGGAAGCTTGCGCAGGCGCAGCA
CCGTTCCACGCACTACCTGATGCGCGAGGCTATCGCGCAATATGTTGAGCGTGAGGAAAAGCGTGCGGCGTTTCGGCAGG
ATGCTTTGGAGGCGTGGTCTGCTTATCAGGCGAGTGGATCGCATCTCAATCAGACAGAAGCCGATGAGTGGTTGGCCAAG
CTTGAGGCCGGGCAGGACGTGGAACCGCCTGAATGCCACAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4D7DZI7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4D7DSM4

References