124196

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 997949..998514 Replicon chromosome
Accession NZ_CP039691
Organism Agrobacterium larrymoorei strain CFBP5473

Toxin (Protein)


Gene name parE Uniprot ID A0A4D7DZI7
Locus tag CFBP5473_RS04705 Protein ID WP_027674231.1
Coordinates 998221..998514 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4D7DSM4
Locus tag CFBP5473_RS04700 Protein ID WP_027674230.1
Coordinates 997949..998233 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5473_RS04670 993665..994312 + 648 WP_027674224.1 CoA pyrophosphatase -
CFBP5473_RS04675 994309..995556 + 1248 WP_027674225.1 CCA tRNA nucleotidyltransferase -
CFBP5473_RS04680 995786..995974 - 189 WP_027674226.1 DUF1059 domain-containing protein -
CFBP5473_RS04685 996126..996392 - 267 WP_027674227.1 hypothetical protein -
CFBP5473_RS04690 996559..997470 - 912 WP_027674228.1 oxygen-dependent coproporphyrinogen oxidase -
CFBP5473_RS04695 997596..997871 + 276 WP_027674229.1 hypothetical protein -
CFBP5473_RS04700 997949..998233 + 285 WP_027674230.1 ribbon-helix-helix protein, CopG family Antitoxin
CFBP5473_RS04705 998221..998514 + 294 WP_027674231.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5473_RS04710 998540..1000192 - 1653 WP_027674232.1 Na/Pi cotransporter family protein -
CFBP5473_RS04715 1000424..1000885 - 462 WP_027674233.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
CFBP5473_RS04720 1001300..1003156 + 1857 WP_027674234.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11037.89 Da        Isoelectric Point: 9.5450

>T124196 WP_027674231.1 NZ_CP039691:998221-998514 [Agrobacterium larrymoorei]
MPQLIWTPEALRDVQRCYRFLAPKNPDAASRAIKSIREKMRMIVTHPAIGRPVDKMAPEFRELLIPFGESGYVALYRLDG
DLAVVLAVRHQNEAGYT

Download         Length: 294 bp

>T124196 NZ_CP039691:998221-998514 [Agrobacterium larrymoorei]
ATGCCACAACTGATCTGGACGCCAGAAGCACTCAGGGACGTTCAGCGCTGTTATCGTTTTCTTGCCCCGAAAAATCCAGA
TGCTGCATCTCGGGCGATAAAGTCCATTCGCGAAAAGATGCGGATGATCGTGACGCATCCGGCCATTGGCCGCCCCGTCG
ACAAGATGGCCCCGGAATTTCGGGAATTGCTTATTCCGTTTGGTGAGAGCGGCTATGTCGCGCTTTACCGTTTGGATGGT
GATCTGGCCGTGGTTTTGGCCGTGCGTCATCAAAATGAAGCTGGTTACACCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10729.96 Da        Isoelectric Point: 6.2152

>AT124196 WP_027674230.1 NZ_CP039691:997949-998233 [Agrobacterium larrymoorei]
MPGPHPVAVKLDPEVHARMRKLAQAQHRSTHYLMREAIAQYVEREEKRAAFRQDALEAWSAYQASGSHLNQTEADEWLAK
LEAGQDVEPPECHN

Download         Length: 285 bp

>AT124196 NZ_CP039691:997949-998233 [Agrobacterium larrymoorei]
ATGCCGGGACCACATCCAGTTGCGGTGAAGCTCGATCCGGAGGTCCACGCCCGGATGCGGAAGCTTGCGCAGGCGCAGCA
CCGTTCCACGCACTACCTGATGCGCGAGGCTATCGCGCAATATGTTGAGCGTGAGGAAAAGCGTGCGGCGTTTCGGCAGG
ATGCTTTGGAGGCGTGGTCTGCTTATCAGGCGAGTGGATCGCATCTCAATCAGACAGAAGCCGATGAGTGGTTGGCCAAG
CTTGAGGCCGGGCAGGACGTGGAACCGCCTGAATGCCACAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D7DZI7

Antitoxin

Source ID Structure
AlphaFold DB A0A4D7DSM4

References