Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 828206..828791 Replicon chromosome
Accession NZ_CP039691
Organism Agrobacterium larrymoorei strain CFBP5473

Toxin (Protein)


Gene name PumA Uniprot ID A0A4D7DTW6
Locus tag CFBP5473_RS03875 Protein ID WP_027676625.1
Coordinates 828504..828791 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFBP5473_RS03870 Protein ID WP_027676624.1
Coordinates 828206..828502 (-) Length 99 a.a.

Genomic Context

CFBP5473_RS03865CFBP5473_RS03850CFBP5473_RS03855CFBP5473_RS03860CFBP5473_RS03870CFBP5473_RS03875CFBP5473_RS03880CFBP5473_RS03885CFBP5473_RS03895
Location: 827961..828191 (231 bp)
Type: Others
Protein ID: WP_027676623.1
Location: 824297..825604 (1308 bp)
Type: Others
Protein ID: WP_027676620.1
Location: 825601..826848 (1248 bp)
Type: Others
Protein ID: WP_027676621.1
Location: 826963..827856 (894 bp)
Type: Others
Protein ID: WP_027676622.1
Location: 828206..828502 (297 bp)
Type: Antitoxin
Protein ID: WP_027676624.1
Location: 828504..828791 (288 bp)
Type: Toxin
Protein ID: WP_027676625.1
Location: 828839..829666 (828 bp)
Type: Others
Protein ID: WP_027676626.1
Location: 829676..832015 (2340 bp)
Type: Others
Protein ID: WP_027676627.1
Location: 832202..833668 (1467 bp)
Type: Others
Protein ID: WP_027676628.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFBP5473_RS03850824297..825604-1308WP_027676620.1guanine deaminase-
CFBP5473_RS03855825601..826848-1248WP_027676621.1urate hydroxylase PuuD-
CFBP5473_RS03860826963..827856-894WP_027676622.1transcriptional regulator GcvA-
CFBP5473_RS03865827961..828191+231WP_027676623.1hypothetical protein-
CFBP5473_RS03870828206..828502-297WP_027676624.1putative addiction module antidote proteinAntitoxin
CFBP5473_RS03875828504..828791-288WP_027676625.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CFBP5473_RS03880828839..829666-828WP_027676626.1xanthine dehydrogenase accessory protein XdhC-
CFBP5473_RS03885829676..832015-2340WP_027676627.1xanthine dehydrogenase molybdopterin binding subunit-
CFBP5473_RS03895832202..833668-1467WP_027676628.1xanthine dehydrogenase small subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11008.78 Da        Isoelectric Point: 10.5155

>T124195 WP_027676625.1 NZ_CP039691:c828791-828504 [Agrobacterium larrymoorei]
MIRIRKTNIFSDWFTSLRDKRAQARIQVRIDRLSLGLLGDVKFFDGIGEMRIDYGPGYRVYFTRRQNEIVILLCGGDKGS
QTRDIERAIKIAAEV

Download         Length: 288 bp

>T124195 NZ_CP039691:c828791-828504 [Agrobacterium larrymoorei]
ATGATCAGAATTCGGAAAACGAATATCTTCTCGGACTGGTTTACGTCCCTGCGAGATAAAAGAGCGCAAGCAAGGATTCA
GGTTCGTATTGACCGTCTTTCGCTGGGACTTCTCGGCGACGTGAAATTTTTCGATGGCATTGGCGAAATGCGGATCGATT
ACGGGCCGGGCTACCGGGTTTATTTCACGCGAAGGCAAAACGAGATAGTTATTCTGCTGTGCGGTGGAGACAAGGGATCT
CAGACGAGAGACATCGAACGCGCCATCAAGATTGCAGCCGAGGTTTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10458.02 Da        Isoelectric Point: 4.8146

>AT124195 WP_027676624.1 NZ_CP039691:c828502-828206 [Agrobacterium larrymoorei]
MKVEVTDWDTSDYLNGNEAVIAYLEASFEDGDPKVIAMALGNIAKAKGMSQVAKQAGITREALYKSLSEKGDPKLSTLIG
VMKALGLRLSVAPEERAA

Download         Length: 297 bp

>AT124195 NZ_CP039691:c828502-828206 [Agrobacterium larrymoorei]
ATGAAAGTAGAAGTGACCGATTGGGATACGAGCGATTACCTCAATGGCAATGAAGCCGTGATCGCCTATCTGGAAGCCTC
GTTCGAGGATGGCGATCCGAAGGTCATTGCCATGGCCCTCGGCAACATCGCGAAAGCCAAAGGCATGAGCCAGGTCGCCA
AGCAAGCGGGCATTACCCGGGAAGCGCTTTATAAGTCGCTCAGTGAAAAGGGCGACCCCAAGCTTTCGACCCTCATCGGA
GTGATGAAGGCGTTAGGCTTACGTCTTTCGGTCGCCCCTGAAGAAAGAGCCGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4D7DTW6

Antitoxin

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Source
ID
Structure
No matching records found

References