124190

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 1673331..1673971 Replicon chromosome
Accession NZ_CP039690
Organism Phreatobacter stygius strain KCTC 52518

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E8M01_RS07640 Protein ID WP_136959584.1
Coordinates 1673615..1673971 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag E8M01_RS07635 Protein ID WP_136959583.1
Coordinates 1673331..1673618 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E8M01_RS07620 1670071..1670856 + 786 WP_136959580.1 3-ketoacyl-ACP reductase -
E8M01_RS07625 1670887..1671384 + 498 WP_136959581.1 MaoC family dehydratase N-terminal domain-containing protein -
E8M01_RS07630 1671581..1673206 + 1626 WP_136959582.1 ABC transporter substrate-binding protein -
E8M01_RS07635 1673331..1673618 + 288 WP_136959583.1 hypothetical protein Antitoxin
E8M01_RS07640 1673615..1673971 + 357 WP_136959584.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E8M01_RS07645 1674027..1674887 - 861 WP_136959585.1 transglutaminase-like domain-containing protein -
E8M01_RS07650 1674884..1675888 - 1005 WP_136964498.1 protein BugT -
E8M01_RS07655 1676060..1676905 - 846 WP_136959586.1 amidohydrolase family protein -
E8M01_RS07660 1676902..1677909 - 1008 WP_136959587.1 hydroxyacid dehydrogenase -
E8M01_RS07665 1677906..1678928 - 1023 WP_136959588.1 Gfo/Idh/MocA family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13098.76 Da        Isoelectric Point: 5.6544

>T124190 WP_136959584.1 NZ_CP039690:1673615-1673971 [Phreatobacter stygius]
MRLFWTPEALDDRRAIYDYVEAANPSAALGLDELFSQKASGLLDHPGLGRPGRVAATRELVAHQNYILIYDTAGDLVRIL
RLLHVARQWPPARTVDEARRPDGEPGASSEIAKRDDPP

Download         Length: 357 bp

>T124190 NZ_CP039690:1673615-1673971 [Phreatobacter stygius]
TTGAGGTTGTTCTGGACCCCGGAAGCTCTCGATGATCGCCGTGCGATCTACGATTATGTCGAGGCCGCCAATCCGAGCGC
CGCGCTCGGCCTCGACGAACTGTTTTCGCAGAAGGCCAGCGGTCTTCTCGATCATCCGGGCCTCGGGCGCCCTGGTCGTG
TTGCCGCCACCCGCGAACTGGTCGCGCATCAGAATTACATCCTGATCTACGATACGGCCGGCGACCTCGTCCGTATCCTC
CGTCTGCTGCATGTTGCGAGGCAGTGGCCGCCGGCGAGAACTGTCGATGAGGCCCGTCGACCGGACGGCGAACCAGGCGC
CAGCTCGGAAATCGCAAAACGCGATGATCCGCCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10879.09 Da        Isoelectric Point: 10.4218

>AT124190 WP_136959583.1 NZ_CP039690:1673331-1673618 [Phreatobacter stygius]
MTEATFTFRVEETLKEQFAAAAKSRDRTGAQLLRDFMRDFVRQQQDAAEHDAWFRRQVQAGLDSAAAGRLVANEDVEAEF
ASRRSRTRRKLTTPS

Download         Length: 288 bp

>AT124190 NZ_CP039690:1673331-1673618 [Phreatobacter stygius]
ATGACCGAGGCAACCTTCACTTTCCGTGTCGAGGAGACCCTGAAAGAACAATTCGCCGCGGCGGCAAAGTCCCGCGACCG
CACCGGCGCGCAGCTACTGCGCGACTTCATGCGCGATTTCGTACGGCAGCAGCAGGACGCTGCCGAACATGACGCCTGGT
TCCGTCGCCAGGTCCAGGCTGGGCTGGATTCCGCTGCCGCGGGCCGCCTTGTCGCAAACGAGGATGTGGAAGCGGAATTC
GCCTCTCGCAGGAGCCGGACACGCCGCAAGCTCACCACCCCATCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References