Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 181686..182470 Replicon chromosome
Accession NZ_CP039650
Organism Azospirillum sp. TSA2s

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag E6C67_RS22790 Protein ID WP_136704237.1
Coordinates 181979..182470 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag E6C67_RS22785 Protein ID WP_136704236.1
Coordinates 181686..181982 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6C67_RS22770 178898..179716 + 819 WP_136704233.1 enoyl-CoA hydratase -
E6C67_RS22775 179713..180249 + 537 WP_136704234.1 CoA-binding protein -
E6C67_RS22780 180271..181566 + 1296 WP_136704235.1 O-acetylhomoserine aminocarboxypropyltransferase -
E6C67_RS22785 181686..181982 + 297 WP_136704236.1 DUF1778 domain-containing protein Antitoxin
E6C67_RS22790 181979..182470 + 492 WP_136704237.1 GNAT family N-acetyltransferase Toxin
E6C67_RS22795 182477..183712 - 1236 WP_136704238.1 MFS transporter -
E6C67_RS22805 184225..184569 + 345 WP_136704239.1 hypothetical protein -
E6C67_RS22810 184580..184999 - 420 WP_109149863.1 aminoacyl-tRNA hydrolase -
E6C67_RS22815 184996..185838 - 843 WP_169055066.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
E6C67_RS22820 185961..186269 - 309 WP_136704241.1 AzlD domain-containing protein -
E6C67_RS22825 186262..186990 - 729 WP_136705764.1 AzlC family ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-141)

Antitoxin

Vibrio phage ICP1, Orf50

(8-96)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17655.38 Da        Isoelectric Point: 8.0617

>T124188 WP_136704237.1 NZ_CP039650:181979-182470 [Azospirillum sp. TSA2s]
MTLSAPEPLAPHHRVDLFDSGTPSLDTWLRRRAMANQASGASRTFVACAGDEIAGYYALASSAVAVTDAPERFRRNMPDP
IPVVVLARLAVSRTRQGQGLGRALFRDAALRVVQAADLIGVRGLMVHALSEEAKSFYLRLGLDPSPIDPMMLMVTLADLR
DNL

Download         Length: 492 bp

>T124188 NZ_CP039650:181979-182470 [Azospirillum sp. TSA2s]
ATGACGCTGTCCGCGCCGGAACCGCTTGCGCCCCACCACCGCGTCGATCTGTTCGACTCCGGCACGCCGTCGCTGGACAC
TTGGCTGAGGCGCCGGGCGATGGCAAATCAAGCCAGCGGTGCGTCGCGGACCTTCGTCGCCTGTGCTGGCGATGAAATTG
CCGGCTATTACGCTTTGGCATCAAGCGCGGTGGCGGTCACCGATGCACCGGAACGTTTCCGCCGCAATATGCCCGACCCA
ATCCCGGTGGTAGTGCTGGCGCGGCTCGCCGTTTCGCGGACACGGCAGGGGCAGGGGCTCGGCCGGGCGCTGTTCCGTGA
CGCCGCCCTGCGGGTCGTGCAGGCGGCCGATCTGATCGGCGTCCGCGGATTGATGGTTCACGCATTGTCGGAAGAGGCGA
AGAGCTTTTATCTTCGCCTCGGCCTCGATCCCTCGCCGATTGACCCGATGATGCTGATGGTCACTCTGGCCGACCTGCGG
GACAACCTATAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11131.57 Da        Isoelectric Point: 8.7059

>AT124188 WP_136704236.1 NZ_CP039650:181686-181982 [Azospirillum sp. TSA2s]
MQPVEPSEEKSRRETLNIRIRPEERSLIDRAAQAQGKNRTDFILEAARHAAEDALLDRAIIAAGPDAYAEFLARLDAPPK
PNERLRRTMRTAAPWERG

Download         Length: 297 bp

>AT124188 NZ_CP039650:181686-181982 [Azospirillum sp. TSA2s]
ATGCAGCCTGTCGAACCGTCAGAAGAGAAGTCCCGACGCGAGACGCTCAACATCCGCATCAGGCCGGAGGAGCGCAGCCT
GATCGACCGGGCGGCCCAGGCACAGGGCAAGAACCGCACCGACTTTATCCTGGAAGCGGCTCGCCACGCCGCCGAGGATG
CCCTGCTCGACCGCGCGATTATCGCCGCCGGCCCGGACGCCTATGCCGAGTTCCTGGCCCGTCTCGACGCACCGCCCAAG
CCGAACGAAAGACTGCGCCGGACAATGCGGACAGCCGCCCCCTGGGAGCGCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References