Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 229478..231014 Replicon chromosome
Accession NZ_CP039647
Organism Azospirillum sp. TSA2s

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag E6C67_RS11250 Protein ID WP_211103498.1
Coordinates 229478..230413 (-) Length 312 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag E6C67_RS11255 Protein ID WP_136702612.1
Coordinates 230403..231014 (-) Length 204 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6C67_RS11230 224956..226026 - 1071 WP_136702588.1 IS630 family transposase -
E6C67_RS11235 226858..227301 + 444 WP_136702609.1 TrbG/VirB9 family P-type conjugative transfer protein -
E6C67_RS11240 227305..227754 + 450 WP_136702610.1 conjugal transfer protein TrbH -
E6C67_RS11245 227751..229142 + 1392 WP_136702611.1 conjugal transfer protein TrbI -
E6C67_RS11250 229478..230413 - 936 WP_211103498.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
E6C67_RS11255 230403..231014 - 612 WP_136702612.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
E6C67_RS11260 231308..232003 + 696 WP_136702613.1 IS6 family transposase -
E6C67_RS11265 232208..232747 + 540 WP_136702614.1 conjugal transfer protein TrbI -
E6C67_RS11270 233167..234096 + 930 WP_136702615.1 pirin -
E6C67_RS11275 234357..235220 + 864 WP_211103499.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 224956..226026 1070


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-261)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-54)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 34368.24 Da        Isoelectric Point: 5.9305

>T124185 WP_211103498.1 NZ_CP039647:c230413-229478 [Azospirillum sp. TSA2s]
VTIKPPRNIAASVRQKLLNVAKVRAADFQQIGTQYSLERLLYRISISEHRDRLILKGGLLFLAWQADTARPTRDADFLSF
GSSDTDEMKKAFQSILSLPADDGVQFDLTAIEATRIRPEDEYDGVRVTTNATISGARFPIQVDIGFGDAITPGTQEIHFP
TLLDQPAPRVLSYPPETVIAEKLEAIISLGDINGRLKDFYDLGVISRTFEINGGILAKAIAATFARRKTDLPEAEPPSLM
PAFANLDTTKRNWNAFIRRNTLAVKFASFEALQEELLTFLQPPIAAARTAEALNARWLPEKGWVSTSAIPS

Download         Length: 936 bp

>T124185 NZ_CP039647:c230413-229478 [Azospirillum sp. TSA2s]
GTGACGATTAAGCCCCCCAGAAACATCGCTGCCTCAGTGCGGCAGAAGCTGCTCAACGTGGCCAAAGTCCGCGCTGCCGA
CTTTCAACAGATCGGCACGCAGTACAGTCTGGAACGCTTGCTTTACCGCATCAGCATTTCCGAGCACAGGGACCGCCTTA
TCCTGAAAGGTGGCCTGCTTTTCCTGGCGTGGCAGGCGGATACGGCTCGTCCCACCCGGGACGCCGATTTCCTTTCCTTC
GGTAGCAGTGACACCGATGAGATGAAGAAAGCCTTCCAGAGCATCCTGTCTCTCCCCGCCGACGACGGCGTCCAGTTTGA
CCTGACGGCCATTGAGGCAACGCGCATACGCCCCGAGGACGAGTACGATGGCGTGCGCGTTACGACAAACGCAACAATCT
CCGGAGCACGCTTTCCGATCCAGGTCGATATCGGCTTTGGTGATGCCATCACGCCCGGCACTCAGGAAATCCACTTCCCT
ACGCTTCTGGACCAGCCCGCGCCGCGCGTGCTCTCCTATCCGCCTGAGACGGTCATCGCAGAAAAACTTGAAGCCATCAT
TTCCTTGGGCGACATCAACGGGCGACTCAAAGACTTCTACGATCTTGGGGTTATCAGCCGCACGTTCGAGATCAACGGCG
GCATCCTGGCCAAAGCGATTGCCGCTACCTTTGCCCGGCGCAAAACCGACCTCCCGGAGGCGGAACCACCCAGTCTGATG
CCGGCCTTCGCCAATTTGGACACGACGAAGCGTAACTGGAACGCATTCATTCGCCGCAACACACTCGCCGTCAAGTTCGC
GTCGTTCGAAGCACTGCAGGAAGAGTTGCTCACGTTCCTGCAACCTCCCATCGCGGCGGCACGCACAGCAGAGGCGCTGA
ACGCTCGTTGGCTTCCTGAAAAAGGCTGGGTTTCAACCAGCGCCATTCCTTCATAG

Antitoxin


Download         Length: 204 a.a.        Molecular weight: 22422.28 Da        Isoelectric Point: 9.7913

>AT124185 WP_136702612.1 NZ_CP039647:c231014-230403 [Azospirillum sp. TSA2s]
MGSTRREQVVAFLREHGIARSRDIRALGVPPSTLMRMVENGDVVQLARGLYQLPDTDFDAAHSLAEVARLVPKGVICLIS
ALVYHGLTLQMPSRVWLALPQGTWRPQFAYPPVKTVHMARAAISAGVEHHKIEGVLVPIFSPAKTVADCFKFRSLVGVDV
AIEGMQLALRKRKAKPQEILDHASELRVAKIVRPYLEACISDD

Download         Length: 612 bp

>AT124185 NZ_CP039647:c231014-230403 [Azospirillum sp. TSA2s]
ATGGGCTCCACCAGGCGGGAGCAGGTTGTTGCCTTTCTGCGGGAGCATGGAATTGCACGATCCCGTGACATCAGGGCGCT
TGGAGTGCCCCCTTCAACACTGATGCGGATGGTCGAAAATGGCGACGTGGTCCAACTCGCTCGAGGTCTCTACCAGTTGC
CGGACACCGACTTCGACGCCGCGCACAGCCTCGCTGAAGTGGCAAGGCTGGTTCCCAAAGGCGTTATCTGTCTCATTTCC
GCCCTCGTGTATCATGGCTTGACCTTGCAGATGCCATCGCGCGTTTGGCTTGCTCTGCCGCAAGGGACTTGGCGACCGCA
GTTCGCCTATCCCCCCGTCAAAACCGTCCACATGGCAAGGGCGGCGATCAGCGCCGGAGTGGAACACCATAAGATCGAAG
GGGTACTGGTGCCGATCTTCTCACCAGCCAAGACCGTCGCCGATTGCTTCAAGTTTCGTTCGCTGGTGGGCGTCGATGTG
GCAATCGAGGGAATGCAGTTGGCTTTGAGAAAGCGCAAAGCCAAGCCCCAAGAGATTCTCGACCACGCCTCTGAATTGAG
GGTTGCGAAGATTGTTCGCCCGTATCTCGAGGCCTGCATCAGTGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References