Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 459274..459914 Replicon chromosome
Accession NZ_CP039645
Organism Azospirillum sp. TSA2s

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E6C67_RS06625 Protein ID WP_109073198.1
Coordinates 459274..459690 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E6C67_RS06630 Protein ID WP_136701964.1
Coordinates 459690..459914 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6C67_RS06605 455195..456133 + 939 WP_109073194.1 LysR family transcriptional regulator -
E6C67_RS06610 456157..457719 + 1563 WP_109073195.1 threonine ammonia-lyase, biosynthetic -
E6C67_RS06615 457743..458225 - 483 WP_158281936.1 cupin domain-containing protein -
E6C67_RS06620 458461..459234 + 774 WP_109073197.1 SDR family NAD(P)-dependent oxidoreductase -
E6C67_RS06625 459274..459690 - 417 WP_109073198.1 type II toxin-antitoxin system VapC family toxin Toxin
E6C67_RS06630 459690..459914 - 225 WP_136701964.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
E6C67_RS06635 460100..461584 + 1485 WP_109073200.1 L-lactate permease -
E6C67_RS06640 461594..462469 - 876 WP_169054811.1 DMT family transporter -
E6C67_RS06645 462606..464072 + 1467 WP_136701965.1 PLP-dependent aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15416.54 Da        Isoelectric Point: 6.0974

>T124184 WP_109073198.1 NZ_CP039645:c459690-459274 [Azospirillum sp. TSA2s]
MLRYMLDTNVCIRVLRDRPQSARVRFNAEADGLCISTVTLAELLHGAAKSDHPAEKRREVERLTARLEVLPFDDEAAGHY
GDIRADLERRGCVIGPYDLMIAGHARSRGLVVITGNLGEFDRVAGLRCEDWLDEPRGS

Download         Length: 417 bp

>T124184 NZ_CP039645:c459690-459274 [Azospirillum sp. TSA2s]
ATGCTGCGCTACATGCTGGACACCAATGTCTGTATCCGCGTCCTGCGCGACCGTCCACAGAGTGCCCGCGTCAGGTTCAA
TGCGGAGGCGGACGGCCTGTGCATCTCGACGGTGACGCTGGCGGAACTTCTGCACGGTGCGGCCAAATCCGACCACCCGG
CCGAGAAACGCCGGGAGGTCGAACGGCTGACCGCCCGACTGGAGGTGCTGCCCTTCGACGACGAGGCGGCCGGACATTAC
GGGGACATCCGGGCCGATCTGGAGCGCCGGGGCTGCGTGATCGGCCCGTATGATCTGATGATCGCCGGCCATGCGCGCAG
CCGCGGACTCGTCGTGATCACGGGTAATCTTGGCGAGTTCGACCGTGTGGCGGGCCTGCGGTGCGAGGACTGGCTGGACG
AACCGCGTGGGTCCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8583.71 Da        Isoelectric Point: 5.7810

>AT124184 WP_136701964.1 NZ_CP039645:c459914-459690 [Azospirillum sp. TSA2s]
MTVRTSLFQSNRTQAVRLPKDVSFPAHVREVVILRDGARRLIVPADSVWDDFFQSPGIAFPDRDQPEMQEREAW

Download         Length: 225 bp

>AT124184 NZ_CP039645:c459914-459690 [Azospirillum sp. TSA2s]
ATGACGGTCCGGACGTCCCTGTTCCAGTCCAACCGCACTCAGGCCGTTCGTCTGCCCAAGGACGTGTCGTTTCCTGCGCA
TGTCCGCGAGGTGGTCATCCTGCGTGATGGCGCGCGGCGGCTGATCGTGCCGGCCGATAGCGTGTGGGACGATTTCTTCC
AGTCTCCCGGCATCGCTTTCCCCGACCGCGACCAGCCGGAGATGCAGGAACGCGAGGCGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References