Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 135105..135736 Replicon chromosome
Accession NZ_CP039637
Organism Azospirillum sp. TSH100

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E6C72_RS22230 Protein ID WP_109085217.1
Coordinates 135105..135512 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E6C72_RS22235 Protein ID WP_109085216.1
Coordinates 135512..135736 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6C72_RS22215 130676..132574 - 1899 WP_109085275.1 TRAP transporter large permease subunit -
E6C72_RS22220 132624..133664 - 1041 WP_109085219.1 TRAP transporter substrate-binding protein -
E6C72_RS22225 133805..134893 + 1089 WP_109085218.1 LacI family DNA-binding transcriptional regulator -
E6C72_RS22230 135105..135512 - 408 WP_109085217.1 tRNA(fMet)-specific endonuclease VapC Toxin
E6C72_RS22235 135512..135736 - 225 WP_109085216.1 antitoxin Antitoxin
E6C72_RS22240 135882..139073 - 3192 WP_109085215.1 multidrug efflux RND transporter permease subunit -
E6C72_RS22245 139162..140325 - 1164 WP_109085214.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(8-55)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15056.24 Da        Isoelectric Point: 6.8647

>T124182 WP_109085217.1 NZ_CP039637:c135512-135105 [Azospirillum sp. TSH100]
MLRYMLDTNLCIRVLRDRPPGLRGKFNAETGALCISTVTLAELLHGAAKSARPIEQRHEVERMTGRLEVLPFDEDAAGHY
GEIRADLERRGTIIGPYDLMIAAHARSRGLVVVTGNLGEFRRVDGLRSEDWLSDA

Download         Length: 408 bp

>T124182 NZ_CP039637:c135512-135105 [Azospirillum sp. TSH100]
ATGCTGCGCTACATGCTGGATACCAACCTGTGCATCCGCGTGCTGCGTGACAGGCCTCCCGGCCTGCGCGGGAAATTCAA
CGCGGAAACGGGCGCGCTCTGCATCTCCACCGTCACGCTGGCCGAGCTGCTGCATGGCGCTGCCAAATCGGCGCGGCCAA
TCGAGCAGCGCCATGAGGTCGAGCGCATGACAGGTCGACTGGAGGTGCTTCCATTCGACGAGGATGCGGCCGGGCACTAT
GGTGAGATCCGCGCCGACCTTGAGCGTCGCGGCACCATCATCGGACCCTACGATCTGATGATCGCCGCGCACGCCCGCAG
CCGCGGCCTGGTCGTCGTGACGGGAAATCTGGGTGAGTTTCGACGTGTCGATGGCCTTCGGTCGGAAGATTGGCTCAGCG
ACGCCTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8440.57 Da        Isoelectric Point: 4.7266

>AT124182 WP_109085216.1 NZ_CP039637:c135736-135512 [Azospirillum sp. TSH100]
MAVRTTLFQSNRTQAVRLPKDVAFPGDVREVLIVREGDRRVIVPADRAWDDFFDAPGIAFPDRDQPAMQEREAL

Download         Length: 225 bp

>AT124182 NZ_CP039637:c135736-135512 [Azospirillum sp. TSH100]
ATGGCGGTCCGCACTACCCTGTTTCAGTCCAACAGGACCCAGGCGGTCCGCCTGCCGAAGGATGTCGCCTTCCCCGGCGA
TGTCCGCGAGGTGCTGATCGTTCGCGAAGGCGACCGGCGCGTCATCGTCCCCGCCGACCGTGCCTGGGACGACTTCTTCG
ACGCTCCCGGCATCGCCTTTCCGGACCGTGACCAGCCGGCCATGCAGGAACGCGAGGCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References