Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4624625..4625275 Replicon chromosome
Accession NZ_CP039546
Organism Methylorubrum populi strain YC-XJ1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E8E01_RS21840 Protein ID WP_186442326.1
Coordinates 4625021..4625275 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E8E01_RS21835 Protein ID WP_012456436.1
Coordinates 4624625..4624999 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E8E01_RS21815 4620393..4620923 - 531 WP_141953666.1 GNAT family N-acetyltransferase -
E8E01_RS21820 4621101..4621529 + 429 WP_141953667.1 DUF983 domain-containing protein -
E8E01_RS21825 4621605..4623344 - 1740 WP_012456434.1 L-lactate permease -
E8E01_RS21830 4623649..4624572 + 924 WP_012456435.1 manganese catalase family protein -
E8E01_RS21835 4624625..4624999 - 375 WP_012456436.1 helix-turn-helix transcriptional regulator Antitoxin
E8E01_RS21840 4625021..4625275 - 255 WP_186442326.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E8E01_RS21845 4625365..4626261 - 897 WP_141953671.1 squalene/phytoene synthase family protein -
E8E01_RS21850 4626291..4626689 - 399 WP_012456439.1 membrane protein -
E8E01_RS21855 4626808..4627752 - 945 WP_012456440.1 protein translocase subunit SecF -
E8E01_RS21860 4627858..4629459 - 1602 WP_012456441.1 protein translocase subunit SecD -
E8E01_RS21865 4629524..4629856 - 333 WP_012456442.1 preprotein translocase subunit YajC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(71-122)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9333.94 Da        Isoelectric Point: 10.4490

>T124103 WP_186442326.1 NZ_CP039546:c4625275-4625021 [Methylorubrum populi]
MAEVVYSKAALRALIRLPTDVSRKIRLKIEQYAAKPESLANNVKALRGEPGVLRLRVGDWRVLFTEEGTVVAVIKIAPRG
DAYD

Download         Length: 255 bp

>T124103 NZ_CP039546:c4625275-4625021 [Methylorubrum populi]
ATGGCTGAAGTCGTCTACAGCAAAGCTGCCTTGAGGGCTTTGATCCGACTTCCCACCGATGTGTCTCGGAAGATCCGCCT
CAAGATCGAGCAATACGCGGCCAAACCCGAGTCACTCGCCAACAACGTGAAAGCGCTTCGAGGCGAGCCCGGCGTCCTGC
GTCTGCGGGTCGGAGATTGGCGCGTGCTCTTCACCGAGGAAGGCACCGTGGTTGCCGTCATCAAGATCGCACCACGGGGT
GACGCCTACGACTGA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 13171.88 Da        Isoelectric Point: 4.6361

>AT124103 WP_012456436.1 NZ_CP039546:c4624999-4624625 [Methylorubrum populi]
MNTRIIITPGGERLVLVPEADFEALVAAAEDNADRTAVAEFRRKLAAGEEELIPASVVERLVSGENRVRVWREHRGLTGA
ALAKQAGLAQAYLSQIETGAREGTVETYSKLAAALGVSLDDLAG

Download         Length: 375 bp

>AT124103 NZ_CP039546:c4624999-4624625 [Methylorubrum populi]
ATGAACACGCGGATCATCATCACCCCCGGCGGCGAGCGTCTCGTGCTGGTGCCCGAGGCAGACTTCGAAGCGCTGGTGGC
AGCGGCCGAAGACAACGCCGACCGCACCGCCGTGGCGGAGTTCCGTCGCAAGCTCGCCGCGGGCGAGGAGGAGCTGATCC
CGGCTTCCGTCGTGGAGCGTCTCGTCTCCGGCGAGAATCGTGTCCGTGTCTGGCGCGAGCACCGGGGCCTGACTGGAGCC
GCGCTGGCGAAGCAGGCAGGTCTCGCACAGGCTTACCTGTCGCAGATCGAGACCGGGGCACGGGAAGGCACGGTGGAAAC
CTACAGCAAGCTTGCCGCGGCCCTGGGCGTTTCCCTGGACGATCTCGCCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References