Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 121713..122358 Replicon chromosome
Accession NZ_CP039517
Organism Salinivibrio sp. YCSC6

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag E8E00_RS14410 Protein ID WP_069363033.1
Coordinates 121960..122358 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag E8E00_RS14405 Protein ID WP_096632489.1
Coordinates 121713..121946 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E8E00_RS14385 117201..119648 + 2448 WP_136588398.1 DUF2309 domain-containing protein -
E8E00_RS14390 119657..120628 + 972 WP_096632498.1 threonylcarbamoyl-AMP synthase -
E8E00_RS14395 120621..121040 - 420 WP_096632495.1 PaaI family thioesterase -
E8E00_RS14400 121033..121542 - 510 WP_168174093.1 NifB/NifX family molybdenum-iron cluster-binding protein -
E8E00_RS14405 121713..121946 + 234 WP_096632489.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
E8E00_RS14410 121960..122358 + 399 WP_069363033.1 type II toxin-antitoxin system VapC family toxin Toxin
E8E00_RS14415 122390..122671 - 282 WP_021023566.1 DUF134 domain-containing protein -
E8E00_RS14420 122785..124233 - 1449 WP_096632486.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
E8E00_RS14425 124245..124970 - 726 WP_096632483.1 6-phosphogluconolactonase -
E8E00_RS14430 124967..126469 - 1503 WP_069589414.1 glucose-6-phosphate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14542.95 Da        Isoelectric Point: 8.7410

>T124065 WP_069363033.1 NZ_CP039517:121960-122358 [Salinivibrio sp. YCSC6]
MLDTCICSFIMREQPKAVLKKLHTVVGNQHRIVISAITYQEMQYGLLGKKASPKHAVLVDAFLQRIDEILPWDKAAVDAT
TAVKRNLMNKGTPIGGNDTAIAGHAIATGCVLVTNNTREFQRVEGLKLEDWA

Download         Length: 399 bp

>T124065 NZ_CP039517:121960-122358 [Salinivibrio sp. YCSC6]
ATGCTTGATACATGTATTTGTTCATTCATTATGAGAGAGCAACCCAAAGCGGTGTTGAAAAAGCTTCACACTGTTGTCGG
CAATCAACATCGCATTGTTATCTCAGCCATTACCTATCAAGAAATGCAATACGGGTTGTTAGGAAAAAAAGCATCACCAA
AACATGCCGTGCTTGTTGATGCTTTTCTTCAGCGAATCGATGAGATTTTACCTTGGGACAAAGCCGCCGTTGACGCGACA
ACTGCAGTTAAGCGCAACCTAATGAATAAAGGCACCCCTATTGGCGGAAACGACACCGCGATTGCCGGGCACGCCATTGC
GACTGGTTGTGTGCTAGTCACAAACAATACGAGGGAGTTTCAGCGTGTTGAAGGACTGAAACTTGAAGATTGGGCTTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9032.18 Da        Isoelectric Point: 4.8723

>AT124065 WP_096632489.1 NZ_CP039517:121713-121946 [Salinivibrio sp. YCSC6]
MRTISIFKNGKNQAVRLPKDFEFDGVNELEIRKEGDVITLRPARPSWLSFGELEKADSDFMTHREELIKDEGRFNFD

Download         Length: 234 bp

>AT124065 NZ_CP039517:121713-121946 [Salinivibrio sp. YCSC6]
ATGAGAACAATATCCATTTTTAAAAATGGCAAGAACCAAGCGGTACGCTTGCCAAAGGATTTTGAGTTTGACGGTGTTAA
TGAGCTTGAAATTCGTAAAGAGGGGGATGTCATCACCTTACGCCCAGCTCGACCAAGTTGGCTCTCATTTGGCGAGCTCG
AAAAGGCTGATAGTGATTTCATGACCCATCGCGAGGAACTGATCAAAGATGAGGGGCGGTTCAACTTTGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References