Detailed information of TA system TA124063

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 1780827..1781407
• Replicon: chromosome
• Accession: NZ_CP039516
• Organism: Salinivibrio sp. YCSC6

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E8E00_RS08135
• Protein ID: WP_096627896.1
• Coordinates: 1780827..1781129 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: E8E00_RS08140
• Protein ID: WP_096627893.1
• Coordinates: 1781126..1781407 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E8E00_RS08095	1776178..1776918	-	741	WP_096627920.1	SDR family oxidoreductase	-
E8E00_RS08100	1776950..1777345	-	396	WP_096627917.1	GFA family protein	-
E8E00_RS08105	1777342..1777839	-	498	WP_096627914.1	ASCH domain-containing protein	-
E8E00_RS08110	1777861..1778409	-	549	WP_096627911.1	GNAT family N-acetyltransferase	-
E8E00_RS08115	1778466..1778804	-	339	WP_096627908.1	hypothetical protein	-
E8E00_RS08120	1778958..1779644	-	687	WP_168174029.1	GNAT family N-acetyltransferase	-
E8E00_RS08125	1779696..1780043	-	348	WP_096627902.1	hypothetical protein	-
E8E00_RS08135	1780827..1781129	-	303	WP_096627896.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
E8E00_RS08140	1781126..1781407	-	282	WP_096627893.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
E8E00_RS08150	1781693..1781971	+	279	WP_096627890.1	type II toxin-antitoxin system RelE/ParE family toxin	-
E8E00_RS08155	1782017..1782364	-	348	WP_096627887.1	hypothetical protein	-
E8E00_RS08160	1782408..1783040	-	633	WP_096627884.1	type B chloramphenicol O-acetyltransferase	-
E8E00_RS08165	1783379..1783855	-	477	WP_096627880.1	GNAT family N-acetyltransferase	-
E8E00_RS08175	1784440..1784961	-	522	WP_077640757.1	GrpB family protein	-
E8E00_RS08180	1785123..1786067	-	945	WP_069591324.1	D-2-hydroxyacid dehydrogenase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1780248..1796200	15952

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-75)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11313.02 Da
• Isoelectric Point: 4.4992

>T124063 WP_096627896.1 NZ_CP039516:c1781129-1780827 [Salinivibrio sp. YCSC6]
MKIVWSPFALERVEDIALYIAEDNPAAAIQWVDDLFAAVERLADFPKSGRMVPEVGAPRIRELIFGSYRVIYSVKDQIDV
LTVRRSSQLLRMSEIGGDET

Nucleotide

• Length: 303 bp

>T124063 NZ_CP039516:c1781129-1780827 [Salinivibrio sp. YCSC6]
ATGAAGATAGTTTGGTCGCCGTTTGCGCTGGAGCGTGTTGAGGATATTGCTCTGTATATTGCAGAAGATAACCCAGCTGC
TGCGATACAGTGGGTTGATGACTTATTTGCCGCGGTCGAGCGATTGGCTGATTTTCCTAAAAGCGGGCGTATGGTTCCTG
AGGTGGGGGCTCCTCGCATCAGAGAGCTAATATTTGGATCGTATCGGGTAATATACAGCGTCAAAGATCAGATCGATGTA
CTGACAGTACGCCGCAGTAGCCAGTTATTGCGGATGTCCGAGATCGGTGGTGACGAAACTTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10706.27 Da
• Isoelectric Point: 7.2060

>AT124063 WP_096627893.1 NZ_CP039516:c1781407-1781126 [Salinivibrio sp. YCSC6]
MSRVRVDEDIRPLSEFRAGVATFVKQIHETRRPMVLTQRGRGVAVLLDVREYEKMQERLEILEDVYKAEEQIASGDGIAH
EDAKARVLSRLAR

Nucleotide

• Length: 282 bp

>AT124063 NZ_CP039516:c1781407-1781126 [Salinivibrio sp. YCSC6]
ATGTCAAGGGTTCGAGTAGATGAAGATATCCGTCCTCTGTCTGAATTTCGAGCAGGTGTAGCGACATTTGTAAAGCAGAT
CCATGAAACGCGTCGTCCTATGGTGCTGACACAAAGAGGCCGTGGTGTTGCCGTACTGTTGGATGTTCGCGAGTACGAGA
AGATGCAGGAACGTCTGGAGATACTGGAAGATGTATATAAGGCGGAAGAACAGATAGCCTCTGGGGATGGTATTGCACAC
GAAGATGCGAAGGCACGTGTTCTGAGCAGGCTGGCTCGATGA