Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 43744..44269 Replicon plasmid pCFSAN000669_1
Accession NZ_CP039494
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000669

Toxin (Protein)


Gene name ccdB Uniprot ID A0A4D6P1W7
Locus tag E3383_RS23225 Protein ID WP_020833585.1
Coordinates 43964..44269 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID I3VZQ6
Locus tag E3383_RS23220 Protein ID WP_000813642.1
Coordinates 43744..43962 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3383_RS23200 39666..40718 + 1053 WP_020833588.1 Ig-like domain-containing protein -
E3383_RS23205 40917..41180 + 264 WP_136555995.1 hypothetical protein -
E3383_RS23210 41247..41765 + 519 WP_186266475.1 LuxR C-terminal-related transcriptional regulator -
E3383_RS23215 42553..42924 + 372 WP_100215268.1 DUF1311 domain-containing protein -
E3383_RS23220 43744..43962 + 219 WP_000813642.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
E3383_RS23225 43964..44269 + 306 WP_020833585.1 type II toxin-antitoxin system toxin CcdB Toxin
E3383_RS23230 44578..45360 + 783 WP_020833584.1 site-specific integrase -
E3383_RS23235 45511..46452 - 942 WP_000728920.1 Rpn family recombination-promoting nuclease/putative transposase -
E3383_RS23240 47083..47337 + 255 WP_001749329.1 hypothetical protein -
E3383_RS23245 48026..49231 + 1206 WP_000427674.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81941 81941


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-82)

Antitoxin

Post-segregation antitoxin CcdA

(8-77)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 13091.77 Da        Isoelectric Point: 12.8043

>T124038 WP_020833585.1 NZ_CP039494:43964-44269 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKK

Download         Length: 306 bp

>T124038 NZ_CP039494:43964-44269 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 9374.72 Da        Isoelectric Point: 12.6573

>AT124038 WP_000813642.1 NZ_CP039494:43744-43962 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 219 bp

>AT124038 NZ_CP039494:43744-43962 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6P1W7

Antitoxin

Source ID Structure
AlphaFold DB A0A600YYQ0

References