Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 43745..44270 Replicon plasmid pCFSAN000700
Accession NZ_CP039492
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000700

Toxin (Protein)


Gene name ccdB Uniprot ID A0A4D6P1W7
Locus tag E3384_RS23215 Protein ID WP_020833585.1
Coordinates 43965..44270 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID I3VZQ6
Locus tag E3384_RS23210 Protein ID WP_000813642.1
Coordinates 43745..43963 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3384_RS23195 39666..40718 + 1053 WP_020833588.1 Ig-like domain-containing protein -
E3384_RS23200 41119..41766 + 648 WP_186269177.1 autoinducer binding domain-containing protein -
E3384_RS23205 42554..42925 + 372 WP_100215268.1 DUF1311 domain-containing protein -
E3384_RS23210 43745..43963 + 219 WP_000813642.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
E3384_RS23215 43965..44270 + 306 WP_020833585.1 type II toxin-antitoxin system toxin CcdB Toxin
E3384_RS23220 44579..45361 + 783 WP_020833584.1 site-specific integrase -
E3384_RS23225 45512..46453 - 942 WP_000728920.1 Rpn family recombination-promoting nuclease/putative transposase -
E3384_RS23230 47084..47338 + 255 WP_001749329.1 hypothetical protein -
E3384_RS23235 48027..49232 + 1206 WP_000427674.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81941 81941


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 13091.77 Da        Isoelectric Point: 12.8043

>T124036 WP_020833585.1 NZ_CP039492:43965-44270 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKK

Download         Length: 306 bp

>T124036 NZ_CP039492:43965-44270 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 9374.72 Da        Isoelectric Point: 12.6573

>AT124036 WP_000813642.1 NZ_CP039492:43745-43963 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 219 bp

>AT124036 NZ_CP039492:43745-43963 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6P1W7

Antitoxin

Source ID Structure
AlphaFold DB A0A600YYQ0

References