Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 43907..44454 Replicon plasmid pCFSAN000952
Accession NZ_CP039485
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000952

Toxin (Protein)


Gene name parE Uniprot ID A0A4D6NZF1
Locus tag E3399_RS23250 Protein ID WP_000970006.1
Coordinates 43907..44188 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A4D6P197
Locus tag E3399_RS23255 Protein ID WP_000084547.1
Coordinates 44185..44454 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3399_RS23230 39215..39916 - 702 WP_023251326.1 transcriptional activator SprB -
E3399_RS23235 40113..41102 - 990 WP_136556038.1 helix-turn-helix transcriptional regulator -
E3399_RS23240 41411..41920 - 510 WP_131535394.1 hypothetical protein -
E3399_RS23245 43165..43755 + 591 WP_031607984.1 plasmid pRiA4b ORF-3 family protein -
E3399_RS23250 43907..44188 - 282 WP_000970006.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
E3399_RS23255 44185..44454 - 270 WP_000084547.1 hypothetical protein Antitoxin
E3399_RS23265 45410..46291 - 882 WP_023193063.1 incFII family plasmid replication initiator RepA -
E3399_RS23270 46272..46349 - 78 WP_001541552.1 RepA leader peptide Tap -
E3399_RS23275 46599..46865 - 267 WP_001576653.1 replication regulatory protein RepA -
E3399_RS23280 47009..47479 - 471 Protein_52 phospholipase D family protein -
E3399_RS23285 47719..48450 - 732 WP_020833545.1 type-F conjugative transfer system pilin acetylase TraX -
E3399_RS23290 48447..49013 - 567 WP_000493830.1 DUF2726 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81929 81929


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T124032 WP_000970006.1 NZ_CP039485:c44188-43907 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T124032 NZ_CP039485:c44188-43907 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>AT124032 WP_000084547.1 NZ_CP039485:c44454-44185 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp

>AT124032 NZ_CP039485:c44454-44185 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6NZF1

Antitoxin

Source ID Structure
AlphaFold DB A0A4D6P197

References