Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 12396..12955 Replicon plasmid pCFSAN000968_2
Accession NZ_CP039475
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000968

Toxin (Protein)


Gene name relE Uniprot ID S1PMX5
Locus tag E3396_RS23545 Protein ID WP_000421257.1
Coordinates 12396..12671 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5I3EQ05
Locus tag E3396_RS23550 Protein ID WP_001674495.1
Coordinates 12671..12955 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3396_RS23515 8000..9228 + 1229 WP_113708090.1 IS3-like element IS2 family transposase -
E3396_RS23520 9766..10114 + 349 Protein_12 hypothetical protein -
E3396_RS23525 10388..10990 + 603 WP_031618784.1 proQ/FINO family protein -
E3396_RS23530 11046..11546 + 501 WP_024230392.1 hypothetical protein -
E3396_RS23535 11551..11817 + 267 WP_021576094.1 hypothetical protein -
E3396_RS23540 12009..12290 - 282 WP_031618783.1 hypothetical protein -
E3396_RS23545 12396..12671 - 276 WP_000421257.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E3396_RS23550 12671..12955 - 285 WP_001674495.1 ribbon-helix-helix protein, CopG family Antitoxin
E3396_RS23570 13863..14894 - 1032 WP_000907863.1 replication initiation protein -
E3396_RS23585 15867..16130 + 264 Protein_20 ash family protein -
E3396_RS23590 16048..16335 + 288 WP_000074853.1 hypothetical protein -
E3396_RS23600 16777..17310 + 534 WP_001372168.1 transcription termination factor NusG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..95348 95348


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 13558.26 Da        Isoelectric Point: 5.5500

>T124025 WP_000421257.1 NZ_CP039475:c12671-12396 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFF

Download         Length: 276 bp

>T124025 NZ_CP039475:c12671-12396 [Salmonella enterica subsp. enterica serovar Bareilly str.]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Antitoxin


Download         Length: 95 a.a.        Molecular weight: 13999.79 Da        Isoelectric Point: 5.5500

>AT124025 WP_001674495.1 NZ_CP039475:c12955-12671 [Salmonella enterica subsp. enterica serovar Bareilly str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Download         Length: 285 bp

>AT124025 NZ_CP039475:c12955-12671 [Salmonella enterica subsp. enterica serovar Bareilly str.]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1PMX5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I3EQ05

References