Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 61705..62230 Replicon plasmid pCFSAN000970
Accession NZ_CP039472
Organism Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000970

Toxin (Protein)


Gene name ccdB Uniprot ID A0A4D6P1W7
Locus tag E3397_RS23335 Protein ID WP_020833585.1
Coordinates 61925..62230 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID I3VZQ6
Locus tag E3397_RS23330 Protein ID WP_000813642.1
Coordinates 61705..61923 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3397_RS23315 57753..58805 + 1053 WP_020833588.1 Ig-like domain-containing protein -
E3397_RS23320 59004..59726 + 723 WP_000742239.1 LuxR C-terminal-related transcriptional regulator -
E3397_RS23325 60514..60885 + 372 WP_100215268.1 DUF1311 domain-containing protein -
E3397_RS23330 61705..61923 + 219 WP_000813642.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
E3397_RS23335 61925..62230 + 306 WP_020833585.1 type II toxin-antitoxin system toxin CcdB Toxin
E3397_RS23340 62539..63321 + 783 WP_020833584.1 site-specific integrase -
E3397_RS23345 63472..64413 - 942 WP_000728920.1 Rpn family recombination-promoting nuclease/putative transposase -
E3397_RS23350 65044..65298 + 255 WP_001749329.1 hypothetical protein -
E3397_RS23355 65987..67192 + 1206 WP_000427674.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81911 81911


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 13091.77 Da        Isoelectric Point: 12.8043

>T124022 WP_020833585.1 NZ_CP039472:61925-62230 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKK

Download         Length: 306 bp

>T124022 NZ_CP039472:61925-62230 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 9374.72 Da        Isoelectric Point: 12.6573

>AT124022 WP_000813642.1 NZ_CP039472:61705-61923 [Salmonella enterica subsp. enterica serovar Bareilly str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 219 bp

>AT124022 NZ_CP039472:61705-61923 [Salmonella enterica subsp. enterica serovar Bareilly str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4D6P1W7

Antitoxin

Source ID Structure
AlphaFold DB A0A600YYQ0

References