Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2520239..2520826 Replicon chromosome
Accession NZ_CP039456
Organism Changchengzhania lutea strain SM1355

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FAF07_RS11335 Protein ID WP_142785212.1
Coordinates 2520527..2520826 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FAF07_RS11330 Protein ID WP_142785211.1
Coordinates 2520239..2520523 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAF07_RS11310 2515592..2517568 + 1977 WP_142785208.1 cell division protein FtsZ -
FAF07_RS11315 2517707..2518156 + 450 WP_142785209.1 GatB/YqeY domain-containing protein -
FAF07_RS11325 2518534..2519805 + 1272 WP_142785210.1 site-specific integrase -
FAF07_RS11330 2520239..2520523 - 285 WP_142785211.1 putative addiction module antidote protein Antitoxin
FAF07_RS11335 2520527..2520826 - 300 WP_142785212.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAF07_RS11340 2521079..2521951 - 873 WP_142785213.1 hypothetical protein -
FAF07_RS11345 2522050..2522841 - 792 WP_142785214.1 alpha/beta hydrolase -
FAF07_RS11350 2522994..2523674 - 681 WP_142785215.1 LytTR family DNA-binding domain-containing protein -
FAF07_RS11355 2523671..2524615 - 945 WP_185956427.1 sensor histidine kinase -
FAF07_RS11360 2525093..2525560 + 468 WP_142785217.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-93)

Antitoxin

Uncharacterized protein HI1420

(9-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11745.85 Da        Isoelectric Point: 10.4870

>T124006 WP_142785212.1 NZ_CP039456:c2520826-2520527 [Changchengzhania lutea]
MFFIEKTNEFDKWLRKLKDFKAKAKILFRIQKLETDEHFGDCKTVGDGIREMRINFAKGYRVYFKEKDGKVIVLLIGGDK
STQQKDIAKAKEIWKKLNK

Download         Length: 300 bp

>T124006 NZ_CP039456:c2520826-2520527 [Changchengzhania lutea]
ATGTTCTTTATTGAGAAAACAAATGAATTTGACAAATGGCTAAGAAAGCTAAAAGACTTTAAAGCAAAGGCGAAAATTTT
GTTCAGAATTCAAAAATTAGAAACTGACGAACATTTTGGCGATTGTAAAACAGTTGGCGACGGAATTCGGGAAATGCGAA
TAAATTTTGCGAAAGGCTACAGAGTTTACTTTAAAGAAAAAGACGGAAAAGTAATTGTATTGCTTATTGGTGGAGATAAA
TCTACTCAGCAAAAAGACATTGCAAAAGCGAAAGAAATTTGGAAAAAATTAAATAAATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10086.64 Da        Isoelectric Point: 5.0351

>AT124006 WP_142785211.1 NZ_CP039456:c2520523-2520239 [Changchengzhania lutea]
MGTSRFEIADYLDSKEMIAEYLNTVLEEGNNADIINAIGHIAKAIGMTKIAEETGLSRPSLYKALSDGAKPQFATIMKVL
KAIGGQIQVNPMSA

Download         Length: 285 bp

>AT124006 NZ_CP039456:c2520523-2520239 [Changchengzhania lutea]
ATGGGAACTTCAAGATTTGAAATAGCAGATTATTTAGACAGCAAAGAAATGATTGCGGAATATCTCAATACTGTTTTGGA
AGAGGGAAATAATGCGGATATAATTAATGCAATCGGACATATTGCGAAAGCAATCGGAATGACAAAAATTGCGGAGGAAA
CCGGATTAAGCAGACCGAGTTTATACAAAGCATTATCTGATGGAGCGAAACCTCAATTTGCGACAATTATGAAAGTATTA
AAAGCAATCGGAGGACAAATTCAAGTGAATCCAATGTCAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References