Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 74798..75555 Replicon plasmid pCFSAN086834
Accession NZ_CP039444
Organism Salmonella enterica subsp. enterica serovar Infantis strain VNSEC002

Toxin (Protein)


Gene name tacT Uniprot ID A0A241PXX4
Locus tag E8N15_RS23250 Protein ID WP_023994162.1
Coordinates 75073..75555 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A727Z1I8
Locus tag E8N15_RS23245 Protein ID WP_001195098.1
Coordinates 74798..75082 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E8N15_RS23200 70618..70785 - 168 WP_023994170.1 IS66 family insertion sequence element accessory protein TnpB -
E8N15_RS23205 70772..71101 - 330 WP_023994169.1 IS66 family insertion sequence hypothetical protein -
E8N15_RS23210 71234..72078 + 845 Protein_72 site-specific tyrosine recombinase XerC -
E8N15_RS23215 72047..72334 + 288 WP_031619580.1 damage-inducible protein J -
E8N15_RS23220 72331..72636 + 306 WP_023994167.1 type II toxin-antitoxin system RelE/ParE family toxin -
E8N15_RS23225 73223..73649 + 427 Protein_75 DUF977 family protein -
E8N15_RS23230 73675..74010 + 336 WP_023994164.1 hypothetical protein -
E8N15_RS23235 74232..74510 - 279 WP_023994163.1 PIN domain-containing protein -
E8N15_RS23240 74553..74627 + 75 Protein_78 helix-turn-helix domain-containing protein -
E8N15_RS23245 74798..75082 + 285 WP_001195098.1 DUF1778 domain-containing protein Antitoxin
E8N15_RS23250 75073..75555 + 483 WP_023994162.1 GNAT family N-acetyltransferase Toxin
E8N15_RS23255 75870..76296 + 427 Protein_81 transposase -
E8N15_RS23260 76613..76822 + 210 WP_023994160.1 hemolysin expression modulator Hha -
E8N15_RS23265 76896..77248 - 353 Protein_83 transposase -
E8N15_RS23270 77475..78448 + 974 Protein_84 IS256 family transposase -
E8N15_RS23275 78450..78692 + 243 WP_023994156.1 hypothetical protein -
E8N15_RS23280 78763..79719 + 957 WP_023994155.1 Rpn family recombination-promoting nuclease/putative transposase -
E8N15_RS23285 79763..79990 + 228 WP_072205048.1 hypothetical protein -
E8N15_RS23290 80032..80283 - 252 WP_023994153.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..321889 321889


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 20654.05 Da        Isoelectric Point: 13.0041

>T123950 WP_023994162.1 NZ_CP039444:75073-75555 [Salmonella enterica subsp. enterica serovar Infantis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
K

Download         Length: 483 bp

>T123950 NZ_CP039444:75073-75555 [Salmonella enterica subsp. enterica serovar Infantis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT123950 WP_001195098.1 NZ_CP039444:74798-75082 [Salmonella enterica subsp. enterica serovar Infantis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT123950 NZ_CP039444:74798-75082 [Salmonella enterica subsp. enterica serovar Infantis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A241PXX4

Antitoxin

Source ID Structure
AlphaFold DB A0A727Z1I8

References