Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 185359..186116 Replicon plasmid pCFSAN086835
Accession NZ_CP039442
Organism Salmonella enterica subsp. enterica serovar Infantis strain VNSEC003

Toxin (Protein)


Gene name tacT Uniprot ID A0A241PXX4
Locus tag E8N16_RS23735 Protein ID WP_023994162.1
Coordinates 185359..185841 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A727Z1I8
Locus tag E8N16_RS23740 Protein ID WP_001195098.1
Coordinates 185832..186116 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E8N16_RS23695 180631..180882 + 252 WP_023994153.1 helix-turn-helix domain-containing protein -
E8N16_RS23700 180924..181151 - 228 WP_072205048.1 hypothetical protein -
E8N16_RS23705 181195..182151 - 957 WP_023994155.1 Rpn family recombination-promoting nuclease/putative transposase -
E8N16_RS23710 182222..182464 - 243 WP_023994156.1 hypothetical protein -
E8N16_RS23715 182466..183439 - 974 Protein_173 IS256 family transposase -
E8N16_RS23720 183666..184018 + 353 Protein_174 transposase -
E8N16_RS23725 184092..184301 - 210 WP_023994160.1 hemolysin expression modulator Hha -
E8N16_RS23730 184618..185044 - 427 Protein_176 transposase -
E8N16_RS23735 185359..185841 - 483 WP_023994162.1 GNAT family N-acetyltransferase Toxin
E8N16_RS23740 185832..186116 - 285 WP_001195098.1 DUF1778 domain-containing protein Antitoxin
E8N16_RS23745 186287..186361 - 75 Protein_179 helix-turn-helix domain-containing protein -
E8N16_RS23750 186404..186682 + 279 WP_023994163.1 PIN domain-containing protein -
E8N16_RS23755 186904..187239 - 336 WP_023994164.1 hypothetical protein -
E8N16_RS23760 187265..187691 - 427 Protein_182 DUF977 family protein -
E8N16_RS23765 188278..188583 - 306 WP_023994167.1 type II toxin-antitoxin system RelE/ParE family toxin -
E8N16_RS23770 188580..188867 - 288 WP_031619580.1 damage-inducible protein J -
E8N16_RS23775 188836..189680 - 845 Protein_185 site-specific tyrosine recombinase XerC -
E8N16_RS23780 189813..190142 + 330 WP_023994169.1 IS66 family insertion sequence hypothetical protein -
E8N16_RS23785 190129..190296 + 168 WP_023994170.1 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..321887 321887


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 23713.45 Da        Isoelectric Point: 5.5500

>T123946 WP_023994162.1 NZ_CP039442:c185841-185359 [Salmonella enterica subsp. enterica serovar Infantis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Download         Length: 483 bp

>T123946 NZ_CP039442:c185841-185359 [Salmonella enterica subsp. enterica serovar Infantis]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 13999.79 Da        Isoelectric Point: 5.5500

>AT123946 WP_001195098.1 NZ_CP039442:c186116-185832 [Salmonella enterica subsp. enterica serovar Infantis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Download         Length: 285 bp

>AT123946 NZ_CP039442:c186116-185832 [Salmonella enterica subsp. enterica serovar Infantis]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A241PXX4

Antitoxin

Source ID Structure
AlphaFold DB A0A727Z1I8

References