123842

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2197897..2198404 Replicon chromosome
Accession NZ_CP039373
Organism Synechococcus sp. CB0101

Toxin (Protein)


Gene name - Uniprot ID A0A4P7ZUQ6
Locus tag CB0101_RS11815 Protein ID WP_010311145.1
Coordinates 2198141..2198404 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A4P7ZUR7
Locus tag CB0101_RS11810 Protein ID WP_010311146.1
Coordinates 2197897..2198154 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CB0101_RS11780 (CB0101_11765) 2193162..2194220 + 1059 WP_210409954.1 photosystem II q(b) protein -
CB0101_RS11785 (CB0101_11770) 2194338..2194772 - 435 WP_010311155.1 nucleoside deaminase -
CB0101_RS15555 (CB0101_11780) 2195553..2196098 + 546 WP_029553107.1 DUF4351 domain-containing protein -
CB0101_RS11800 (CB0101_11785) 2196126..2197577 - 1452 WP_010311150.1 hypothetical protein -
CB0101_RS11805 (CB0101_11790) 2197680..2197865 + 186 WP_043718058.1 hypothetical protein -
CB0101_RS11810 (CB0101_11795) 2197897..2198154 - 258 WP_010311146.1 hypothetical protein Antitoxin
CB0101_RS11815 (CB0101_11800) 2198141..2198404 - 264 WP_010311145.1 BrnT family toxin Toxin
CB0101_RS11820 (CB0101_11805) 2198599..2199516 + 918 WP_010311141.1 DUF1738 domain-containing protein -
CB0101_RS11825 (CB0101_11810) 2199513..2201858 - 2346 WP_010311139.1 type I restriction endonuclease subunit R -
CB0101_RS11830 (CB0101_11815) 2201855..2202271 - 417 WP_029553106.1 HEPN domain-containing protein -
CB0101_RS11835 (CB0101_11820) 2202225..2202608 - 384 WP_010311133.1 nucleotidyltransferase domain-containing protein -
CB0101_RS11840 (CB0101_11825) 2202671..2202889 - 219 WP_010311131.1 hypothetical protein -
CB0101_RS11845 (CB0101_11830) 2202886..2203312 - 427 Protein_2370 Zeta toxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10183.63 Da        Isoelectric Point: 6.4693

>T123842 WP_010311145.1 NZ_CP039373:c2198404-2198141 [Synechococcus sp. CB0101]
MEFEFDPSKSQSNQEKHGIDFVAAQALWEDPALLEIAARTLDEPRWLVIGRIQRKHWSAVITLRGQAIRLISVRRSRPEE
IQLYEQL

Download         Length: 264 bp

>T123842 NZ_CP039373:c2198404-2198141 [Synechococcus sp. CB0101]
ATGGAGTTTGAGTTCGACCCGAGCAAAAGCCAGTCCAACCAGGAGAAGCACGGCATTGACTTCGTTGCCGCGCAGGCGCT
CTGGGAAGACCCCGCTTTGCTGGAGATCGCCGCGCGCACGCTGGATGAGCCGCGATGGCTCGTCATCGGTCGCATTCAGC
GCAAACACTGGTCAGCGGTGATCACCCTGCGCGGCCAAGCCATCCGACTCATCTCCGTCCGTCGATCACGCCCTGAGGAG
ATTCAGCTCTATGAACAGCTCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9738.94 Da        Isoelectric Point: 6.3062

>AT123842 WP_010311146.1 NZ_CP039373:c2198154-2197897 [Synechococcus sp. CB0101]
MNSSEFDQSFDQGDSVLNSLDLASARRPRLQQKRVNVDFPLWMVEQLDREASRLGVTRQSIIKVWLSERLEPPLAADRPQ
ATGNR

Download         Length: 258 bp

>AT123842 NZ_CP039373:c2198154-2197897 [Synechococcus sp. CB0101]
ATGAACAGCTCTGAGTTTGATCAATCCTTCGATCAGGGCGATTCCGTGCTGAACTCGCTGGATCTCGCCTCCGCCCGGCG
GCCCCGTCTGCAGCAGAAGCGCGTCAATGTCGACTTTCCGCTCTGGATGGTCGAACAACTGGATCGGGAAGCGTCGCGCC
TCGGCGTGACGCGCCAGTCGATCATCAAGGTTTGGCTGTCGGAGCGGTTGGAGCCGCCTCTCGCGGCCGATCGGCCGCAG
GCCACCGGAAACCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7ZUQ6

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7ZUR7

References