123841

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1673999..1674666 Replicon chromosome
Accession NZ_CP039373
Organism Synechococcus sp. CB0101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CB0101_RS08950 Protein ID WP_043718315.1
Coordinates 1673999..1674364 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CB0101_RS08955 Protein ID WP_071778171.1
Coordinates 1674397..1674666 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CB0101_RS08920 (CB0101_08905) 1669176..1669430 + 255 WP_010312477.1 type II toxin-antitoxin system RelE/ParE family toxin -
CB0101_RS08925 (CB0101_08910) 1669438..1670601 - 1164 WP_071778172.1 ATP-binding protein -
CB0101_RS08930 (CB0101_08915) 1670668..1670880 + 213 WP_010312474.1 UPF0175 family protein -
CB0101_RS08935 (CB0101_08920) 1670962..1671942 + 981 WP_136644065.1 IS5 family transposase -
CB0101_RS08940 (CB0101_08925) 1672282..1673260 - 979 Protein_1808 IS5 family transposase -
CB0101_RS08945 (CB0101_08930) 1673562..1674002 - 441 WP_136644066.1 GNAT family N-acetyltransferase -
CB0101_RS08950 (CB0101_08935) 1673999..1674364 - 366 WP_043718315.1 type II toxin-antitoxin system VapC family toxin Toxin
CB0101_RS08955 (CB0101_08940) 1674397..1674666 - 270 WP_071778171.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
CB0101_RS08960 (CB0101_08945) 1674946..1677816 + 2871 WP_010312468.1 preprotein translocase subunit SecA -
CB0101_RS08965 (CB0101_08950) 1677832..1678467 + 636 WP_136644067.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Antitoxin VapB-like

(1-88)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13361.30 Da        Isoelectric Point: 6.4768

>T123841 WP_043718315.1 NZ_CP039373:c1674364-1673999 [Synechococcus sp. CB0101]
MALLLREPEAEALLDRAARTESVLLSAATRLELTLVAEGSCFNSTSADLEALLSNLRVQVVPFNADHMRWALHGWRHYGK
GRHKAALNLGDCFSYGLAKSMDAPLLFKGEDFQYTDVKVPA

Download         Length: 366 bp

>T123841 NZ_CP039373:c1674364-1673999 [Synechococcus sp. CB0101]
ATGGCATTGCTCCTGCGGGAGCCCGAGGCCGAGGCACTCCTCGATCGCGCCGCCCGCACCGAGAGCGTGCTGCTCTCCGC
CGCGACGCGTCTGGAGCTCACGCTGGTGGCGGAAGGCAGCTGTTTCAACAGCACCAGCGCTGATCTCGAAGCTTTACTCA
GCAACTTGCGCGTGCAGGTGGTGCCCTTCAACGCCGACCACATGCGCTGGGCGCTGCACGGCTGGCGCCACTACGGCAAA
GGGCGGCACAAGGCTGCGCTCAATCTTGGCGACTGCTTCAGCTACGGGCTAGCCAAGTCGATGGATGCGCCGCTGCTGTT
CAAGGGCGAGGATTTCCAATACACCGATGTGAAGGTGCCCGCTTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9828.11 Da        Isoelectric Point: 5.1297

>AT123841 WP_071778171.1 NZ_CP039373:c1674666-1674397 [Synechococcus sp. CB0101]
MGMNIKDPQVHAMAKELAARRGTSVTDAVRQALNAELERLPDPLSEASVEARKDAIREICRRTSALPEWQGLNSKQLQDA
LYDENGLPA

Download         Length: 270 bp

>AT123841 NZ_CP039373:c1674666-1674397 [Synechococcus sp. CB0101]
ATGGGAATGAACATCAAGGACCCCCAAGTCCACGCCATGGCCAAGGAGCTGGCGGCCCGCCGAGGCACAAGCGTCACCGA
CGCGGTGCGGCAGGCGCTGAACGCCGAGCTGGAACGGCTGCCGGATCCGCTGAGCGAAGCGAGCGTGGAAGCCCGTAAGG
ACGCTATTCGTGAGATCTGCCGCCGCACCAGCGCCCTGCCCGAATGGCAAGGGCTCAACAGCAAGCAACTCCAGGATGCC
CTCTATGACGAGAACGGGCTGCCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References