Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 5544871..5545460 Replicon chromosome
Accession NZ_CP039371
Organism Pseudomonas putida strain 1290

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E6B08_RS25840 Protein ID WP_136916563.1
Coordinates 5545164..5545460 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag E6B08_RS25835 Protein ID WP_136916562.1
Coordinates 5544871..5545167 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E6B08_RS25820 5541726..5542772 + 1047 WP_136916560.1 hypothetical protein -
E6B08_RS25825 5542983..5543630 + 648 WP_136917491.1 serine protease -
E6B08_RS25830 5543634..5544698 - 1065 WP_136916561.1 diguanylate cyclase -
E6B08_RS25835 5544871..5545167 - 297 WP_136916562.1 putative addiction module antidote protein Antitoxin
E6B08_RS25840 5545164..5545460 - 297 WP_136916563.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E6B08_RS25845 5545679..5546569 + 891 WP_136916564.1 effector protein -
E6B08_RS25850 5546584..5547351 - 768 WP_136916565.1 phosphonate ABC transporter, permease protein PhnE -
E6B08_RS25855 5547348..5548175 - 828 WP_136916566.1 ABC transporter permease -
E6B08_RS25860 5548169..5548963 - 795 WP_136916567.1 ATP-binding cassette domain-containing protein -
E6B08_RS25865 5548960..5549814 - 855 WP_136916568.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10949.68 Da        Isoelectric Point: 11.1951

>T123835 WP_136916563.1 NZ_CP039371:c5545460-5545164 [Pseudomonas putida]
VNHAIAQTRSFSRWWMSLKDTKAKVAIGRRIERIQSGNLGDYKALGGGLGELRIDLGAGYRVYFVRRGETLIFLLAGGDK
SSQTNDIAKARKLIRELK

Download         Length: 297 bp

>T123835 NZ_CP039371:c5545460-5545164 [Pseudomonas putida]
GTGAATCATGCTATAGCGCAGACTAGAAGCTTTTCCCGTTGGTGGATGAGTTTGAAAGACACCAAAGCGAAGGTTGCAAT
CGGTCGCAGGATCGAGCGTATACAAAGCGGAAATCTTGGCGATTACAAGGCGCTTGGCGGAGGGCTTGGTGAGTTGCGGA
TCGATCTTGGTGCTGGTTACCGAGTCTATTTTGTCCGCAGGGGAGAGACACTGATTTTCCTTCTTGCAGGGGGCGACAAG
TCCTCCCAAACCAACGATATAGCGAAAGCCAGAAAACTGATAAGGGAGCTGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10501.04 Da        Isoelectric Point: 5.5802

>AT123835 WP_136916562.1 NZ_CP039371:c5545167-5544871 [Pseudomonas putida]
MSVELIPFDMAAVLDSDEAISEYLSQVLADGDTDEIIRALGHIARARGMGQIAAHSGLGRESLYKALSPGAKPRFDTVLK
VIRALGIDLFAQPHPASR

Download         Length: 297 bp

>AT123835 NZ_CP039371:c5545167-5544871 [Pseudomonas putida]
ATGAGCGTGGAATTGATCCCCTTCGACATGGCCGCTGTGCTCGACAGCGATGAAGCGATCAGCGAATACCTCAGCCAGGT
GCTAGCCGACGGTGATACCGATGAAATCATACGCGCGCTAGGCCATATCGCCAGGGCGCGTGGCATGGGCCAGATTGCGG
CGCACAGCGGTTTGGGGCGAGAGAGTTTGTACAAAGCTCTTAGCCCGGGCGCAAAACCTCGATTCGATACCGTCCTCAAA
GTCATTCGTGCTTTGGGGATCGATCTTTTTGCCCAACCTCATCCTGCCTCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References