Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 19160..19670 Replicon plasmid pTG31302
Accession NZ_CP039344
Organism Acinetobacter baumannii strain TG31302

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EA665_RS19660 Protein ID WP_000827770.1
Coordinates 19410..19670 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EA665_RS19655 Protein ID WP_001024070.1
Coordinates 19160..19420 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EA665_RS19610 14566..15234 - 669 WP_000037012.1 hypothetical protein -
EA665_RS19615 15308..15838 - 531 WP_000219384.1 TIGR02594 family protein -
EA665_RS19620 15819..16070 - 252 WP_001087198.1 hypothetical protein -
EA665_RS19625 16063..16509 - 447 WP_000467408.1 hypothetical protein -
EA665_RS19630 16569..17036 - 468 WP_001123866.1 hypothetical protein -
EA665_RS19635 17029..17559 - 531 WP_000587898.1 DUF2829 domain-containing protein -
EA665_RS19640 17556..18042 - 487 Protein_18 hypothetical protein -
EA665_RS19645 18274..18660 - 387 WP_024432159.1 hypothetical protein -
EA665_RS19655 19160..19420 + 261 WP_001024070.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EA665_RS19660 19410..19670 + 261 WP_000827770.1 Txe/YoeB family addiction module toxin Toxin
EA665_RS19665 19683..19865 + 183 WP_000764644.1 hypothetical protein -
EA665_RS19670 19862..20128 - 267 WP_000312809.1 hypothetical protein -
EA665_RS19675 20118..20717 - 600 WP_000892963.1 hypothetical protein -
EA665_RS19680 20710..20916 - 207 WP_000801902.1 hypothetical protein -
EA665_RS19685 20935..21282 - 348 WP_000827933.1 hypothetical protein -
EA665_RS19690 21279..21557 - 279 WP_000587223.1 hypothetical protein -
EA665_RS19695 21572..21781 - 210 WP_000912547.1 hypothetical protein -
EA665_RS19700 21774..22244 - 471 WP_000224739.1 hypothetical protein -
EA665_RS19705 22270..22785 - 516 WP_000119773.1 hypothetical protein -
EA665_RS19710 22782..23429 - 648 WP_000919094.1 hypothetical protein -
EA665_RS19715 23460..23756 - 297 WP_001181556.1 hypothetical protein -
EA665_RS19720 23911..24639 + 729 WP_001283390.1 XRE family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..55268 55268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10117.52 Da        Isoelectric Point: 8.4866

>T123831 WP_000827770.1 NZ_CP039344:19410-19670 [Acinetobacter baumannii]
MKRNIDFTPTAWDDYLYWQNQDKKTLKRINALIKDCQREPFSGIGKPEGLLGDLSGFWSRRIDEKNRLVYAVDDAAITII
SCRHHY

Download         Length: 261 bp

>T123831 NZ_CP039344:19410-19670 [Acinetobacter baumannii]
ATGAAACGTAATATCGACTTCACCCCTACTGCTTGGGATGATTATTTATATTGGCAAAACCAAGACAAAAAGACGTTAAA
ACGTATTAATGCATTGATTAAAGATTGCCAACGTGAACCATTTAGTGGAATTGGCAAGCCTGAGGGTCTTCTAGGTGATT
TGTCTGGATTCTGGAGCAGACGAATAGATGAAAAAAACCGCTTGGTTTATGCCGTGGATGATGCCGCTATTACAATTATT
TCCTGCAGACACCATTACTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9656.75 Da        Isoelectric Point: 4.4067

>AT123831 WP_001024070.1 NZ_CP039344:19160-19420 [Acinetobacter baumannii]
MNILTYSEARNNLKEVIDQVINDADVTVITRREGQDAVVMGLDHYNSMVETLYLLSNPANSAHLAKSISEYRANKATTRD
LIDDET

Download         Length: 261 bp

>AT123831 NZ_CP039344:19160-19420 [Acinetobacter baumannii]
ATGAACATACTGACTTACAGCGAGGCGAGAAATAATCTCAAAGAGGTTATAGATCAGGTGATTAATGATGCTGACGTGAC
TGTAATTACTAGACGAGAAGGACAGGATGCAGTTGTAATGGGTTTAGATCATTACAATAGTATGGTTGAAACACTATACC
TACTTTCAAATCCAGCTAATTCGGCTCACTTAGCAAAATCAATCTCCGAGTACCGCGCTAATAAAGCAACTACGAGAGAT
TTAATTGACGATGAAACGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References