Detailed information of TA system TA123830

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 471333..471986
• Replicon: chromosome
• Accession: NZ_CP039343
• Organism: Acinetobacter baumannii strain TG31302

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: EA665_RS02370
• Protein ID: WP_000607070.1
• Coordinates: 471597..471986 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: EA665_RS02365
• Protein ID: WP_001288210.1
• Coordinates: 471333..471590 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EA665_RS02345	466849..467856	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
EA665_RS02350	467875..468252	+	378	WP_001216380.1	50S ribosomal protein L17	-
EA665_RS02355	468433..469923	+	1491	WP_000415133.1	NAD(P)/FAD-dependent oxidoreductase	-
EA665_RS02360	469973..471145	-	1173	WP_001190546.1	acyl-CoA dehydrogenase family protein	-
EA665_RS02365	471333..471590	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
EA665_RS02370	471597..471986	+	390	WP_000607070.1	hypothetical protein	Toxin
EA665_RS02375	472756..473841	+	1086	WP_000049107.1	hypothetical protein	-
EA665_RS02380	473919..474485	+	567	WP_000651536.1	rhombosortase	-
EA665_RS02385	474673..476868	+	2196	WP_001158905.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15708.02 Da
• Isoelectric Point: 10.3599

>T123830 WP_000607070.1 NZ_CP039343:471597-471986 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T123830 NZ_CP039343:471597-471986 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTACTTTGAAGATCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT123830 WP_001288210.1 NZ_CP039343:471333-471590 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT123830 NZ_CP039343:471333-471590 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7