Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 28568..29078 Replicon plasmid pTG31986
Accession NZ_CP039342
Organism Acinetobacter baumannii strain TG31986

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EA743_RS19735 Protein ID WP_000827770.1
Coordinates 28818..29078 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EA743_RS19730 Protein ID WP_001024070.1
Coordinates 28568..28828 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EA743_RS19685 23974..24642 - 669 WP_000037012.1 hypothetical protein -
EA743_RS19690 24716..25246 - 531 WP_000219384.1 TIGR02594 family protein -
EA743_RS19695 25227..25478 - 252 WP_001087198.1 hypothetical protein -
EA743_RS19700 25471..25917 - 447 WP_000467408.1 hypothetical protein -
EA743_RS19705 25977..26444 - 468 WP_001123866.1 hypothetical protein -
EA743_RS19710 26437..26967 - 531 WP_000587898.1 DUF2829 domain-containing protein -
EA743_RS19715 26964..27450 - 487 Protein_23 hypothetical protein -
EA743_RS19720 27682..28068 - 387 WP_024432159.1 hypothetical protein -
EA743_RS19730 28568..28828 + 261 WP_001024070.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EA743_RS19735 28818..29078 + 261 WP_000827770.1 Txe/YoeB family addiction module toxin Toxin
EA743_RS19740 29091..29273 + 183 WP_000764644.1 hypothetical protein -
EA743_RS19745 29270..29536 - 267 WP_000312809.1 hypothetical protein -
EA743_RS19750 29526..30125 - 600 WP_000892963.1 hypothetical protein -
EA743_RS19755 30118..30324 - 207 WP_000801902.1 hypothetical protein -
EA743_RS19760 30343..30690 - 348 WP_000827933.1 hypothetical protein -
EA743_RS19765 30687..30965 - 279 WP_000587223.1 hypothetical protein -
EA743_RS19770 30980..31189 - 210 WP_000912547.1 hypothetical protein -
EA743_RS19775 31182..31652 - 471 WP_000224739.1 hypothetical protein -
EA743_RS19780 31678..32193 - 516 WP_000119773.1 hypothetical protein -
EA743_RS19785 32190..32837 - 648 WP_000919094.1 hypothetical protein -
EA743_RS19790 32868..33164 - 297 WP_001181556.1 hypothetical protein -
EA743_RS19795 33319..34047 + 729 WP_001283390.1 XRE family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..55269 55269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10117.52 Da        Isoelectric Point: 8.4866

>T123829 WP_000827770.1 NZ_CP039342:28818-29078 [Acinetobacter baumannii]
MKRNIDFTPTAWDDYLYWQNQDKKTLKRINALIKDCQREPFSGIGKPEGLLGDLSGFWSRRIDEKNRLVYAVDDAAITII
SCRHHY

Download         Length: 261 bp

>T123829 NZ_CP039342:28818-29078 [Acinetobacter baumannii]
ATGAAACGTAATATCGACTTCACCCCTACTGCTTGGGATGATTATTTATATTGGCAAAACCAAGACAAAAAGACGTTAAA
ACGTATTAATGCATTGATTAAAGATTGCCAACGTGAACCATTTAGTGGAATTGGCAAGCCTGAGGGTCTTCTAGGTGATT
TGTCTGGATTCTGGAGCAGACGAATAGATGAAAAAAACCGCTTGGTTTATGCCGTGGATGATGCCGCTATTACAATTATT
TCCTGCAGACACCATTACTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9656.75 Da        Isoelectric Point: 4.4067

>AT123829 WP_001024070.1 NZ_CP039342:28568-28828 [Acinetobacter baumannii]
MNILTYSEARNNLKEVIDQVINDADVTVITRREGQDAVVMGLDHYNSMVETLYLLSNPANSAHLAKSISEYRANKATTRD
LIDDET

Download         Length: 261 bp

>AT123829 NZ_CP039342:28568-28828 [Acinetobacter baumannii]
ATGAACATACTGACTTACAGCGAGGCGAGAAATAATCTCAAAGAGGTTATAGATCAGGTGATTAATGATGCTGACGTGAC
TGTAATTACTAGACGAGAAGGACAGGATGCAGTTGTAATGGGTTTAGATCATTACAATAGTATGGTTGAAACACTATACC
TACTTTCAAATCCAGCTAATTCGGCTCACTTAGCAAAATCAATCTCCGAGTACCGCGCTAATAAAGCAACTACGAGAGAT
TTAATTGACGATGAAACGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References