Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4074165..4074819 Replicon chromosome
Accession NZ_CP039327
Organism Citrobacter portucalensis strain Effluent_1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag E7703_RS19935 Protein ID WP_003825515.1
Coordinates 4074165..4074572 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag E7703_RS19940 Protein ID WP_003825514.1
Coordinates 4074553..4074819 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E7703_RS19915 4070055..4071788 - 1734 WP_048215591.1 single-stranded-DNA-specific exonuclease RecJ -
E7703_RS19920 4071794..4072507 - 714 WP_136392327.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
E7703_RS19925 4072531..4073427 - 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
E7703_RS19930 4073542..4074063 + 522 WP_003026933.1 flavodoxin FldB -
E7703_RS19935 4074165..4074572 - 408 WP_003825515.1 protein YgfX Toxin
E7703_RS19940 4074553..4074819 - 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
E7703_RS19950 4075077..4076060 + 984 WP_136392328.1 tRNA-modifying protein YgfZ -
E7703_RS19955 4076191..4076853 - 663 WP_006686898.1 hemolysin III family protein -
E7703_RS19960 4077017..4077328 - 312 WP_008785743.1 N(4)-acetylcytidine aminohydrolase -
E7703_RS19965 4077381..4078109 + 729 WP_136392531.1 MurR/RpiR family transcriptional regulator -
E7703_RS19970 4078230..4079663 + 1434 WP_128317329.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T123813 WP_003825515.1 NZ_CP039327:c4074572-4074165 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T123813 NZ_CP039327:c4074572-4074165 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
GTTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGTATGATGCTACGCTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGACGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT123813 WP_003825514.1 NZ_CP039327:c4074819-4074553 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT123813 NZ_CP039327:c4074819-4074553 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTTGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTCATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References