Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 880286..881523 Replicon chromosome
Accession NZ_CP039250
Organism Sphingopyxis sp. PAMC25046

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E5675_RS04090 Protein ID WP_136173458.1
Coordinates 880286..880897 (-) Length 204 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E5675_RS04095 Protein ID WP_136173459.1
Coordinates 880978..881523 (-) Length 182 a.a.

Genomic Context

E5675_RS04060E5675_RS04065E5675_RS04070E5675_RS04075E5675_RS04110E5675_RS04080E5675_RS04085E5675_RS04090E5675_RS04095E5675_RS04100E5675_RS04105E5675_RS04115E5675_RS04120E5675_RS04125
Location: 875657..876907 (1251 bp)
Type: Others
Protein ID: WP_136173452.1
Location: 876904..877296 (393 bp)
Type: Others
Protein ID: WP_136173453.1
Location: 877300..877887 (588 bp)
Type: Others
Protein ID: WP_136173454.1
Location: 877892..878371 (480 bp)
Type: Others
Protein ID: WP_136173455.1
Location: 882985..883503 (519 bp)
Type: Others
Protein ID: WP_136173462.1
Location: 878373..878852 (480 bp)
Type: Others
Protein ID: WP_136173456.1
Location: 878836..880155 (1320 bp)
Type: Others
Protein ID: WP_136173457.1
Location: 880286..880897 (612 bp)
Type: Toxin
Protein ID: WP_136173458.1
Location: 880978..881523 (546 bp)
Type: Antitoxin
Protein ID: WP_136173459.1
Location: 881580..882275 (696 bp)
Type: Others
Protein ID: WP_136173460.1
Location: 882268..882732 (465 bp)
Type: Others
Protein ID: WP_136173461.1
Location: 883646..884395 (750 bp)
Type: Others
Protein ID: WP_136173463.1
Location: 884439..885614 (1176 bp)
Type: Others
Protein ID: WP_136173464.1
Location: 885798..886433 (636 bp)
Type: Others
Protein ID: WP_136173465.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E5675_RS04060875657..876907+1251WP_136173452.1threonine ammonia-lyase-
E5675_RS04065876904..877296+393WP_136173453.1acyl-CoA thioesterase-
E5675_RS04070877300..877887+588WP_136173454.1hypothetical protein-
E5675_RS04075877892..878371+480WP_136173455.1GNAT family N-acetyltransferase-
E5675_RS04080878373..878852-480WP_136173456.1MarR family winged helix-turn-helix transcriptional regulator-
E5675_RS04085878836..880155-1320WP_136173457.1S41 family peptidase-
E5675_RS04090880286..880897-612WP_136173458.1HD domain-containing proteinToxin
E5675_RS04095880978..881523-546WP_136173459.1helix-turn-helix domain-containing proteinAntitoxin
E5675_RS04100881580..882275-696WP_136173460.1class I SAM-dependent methyltransferase-
E5675_RS04105882268..882732-465WP_136173461.1Rrf2 family transcriptional regulator-
E5675_RS04110882985..883503+519WP_136173462.1GNAT family N-acetyltransferase-
E5675_RS04115883646..884395-750WP_136173463.1alpha/beta fold hydrolase-
E5675_RS04120884439..885614-1176WP_136173464.1PQQ-dependent sugar dehydrogenase-
E5675_RS04125885798..886433-636WP_136173465.1sigma-70 family RNA polymerase sigma factor-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(22-171)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-56)


Sequences

Toxin        


Download         Length: 204 a.a.        Molecular weight: 22283.61 Da        Isoelectric Point: 5.6210

>T123705 WP_136173458.1 NZ_CP039250:c880897-880286 [Sphingopyxis sp. PAMC25046]
MEQAIQTDPARLEAILAFVQAAEKLKDTLRSGITAQGRAESTAEHSWRLCLMTILFDRELGDHDRLKLLKLCIVHDLGEA
ISGDVPATLQVAGDGRAAQERADLMTLCAPLPDDLRDELVALWDEYSAAATPEAILAKGFDKLETMLQHLVGKNGPGFDY
RFNLAYGAKHTARHPLLAQLRALVDRETQKRVIMMAPAEAAKG

Download         Length: 612 bp

>T123705 NZ_CP039250:c880897-880286 [Sphingopyxis sp. PAMC25046]
ATGGAACAGGCCATTCAGACAGATCCCGCCCGGCTCGAAGCCATCCTCGCTTTCGTCCAGGCGGCCGAGAAGCTCAAGGA
TACGCTGCGGAGCGGCATCACCGCGCAGGGCCGCGCCGAGAGTACCGCCGAACATAGCTGGCGGCTCTGCCTGATGACGA
TCTTGTTCGACCGCGAACTGGGCGATCACGACCGCCTCAAACTGCTCAAGCTGTGTATCGTGCACGACCTCGGCGAAGCG
ATTTCGGGCGACGTTCCGGCAACGCTGCAGGTCGCGGGCGACGGACGCGCCGCGCAGGAACGCGCCGATCTGATGACGTT
GTGCGCCCCATTGCCGGACGACCTCCGCGACGAACTCGTCGCGCTGTGGGACGAATATAGCGCAGCCGCCACGCCCGAGG
CGATCCTCGCCAAGGGCTTCGACAAGCTTGAAACCATGCTCCAGCACCTCGTCGGCAAAAATGGCCCCGGCTTCGACTAC
CGGTTCAACCTCGCCTATGGCGCAAAGCATACCGCGCGCCATCCACTGCTCGCGCAATTGCGCGCCCTCGTCGATCGGGA
AACCCAAAAACGCGTGATAATGATGGCGCCGGCCGAGGCAGCTAAAGGCTGA

Antitoxin


Download         Length: 182 a.a.        Molecular weight: 19525.17 Da        Isoelectric Point: 10.9013

>AT123705 WP_136173459.1 NZ_CP039250:c881523-880978 [Sphingopyxis sp. PAMC25046]
MTQDLPIGRALRRFRRLNAIKQGHFAELLGVAQASVSRWESGTHEPDAAHREKIAALIAAQTGSDADAALKRLVETSTQA
VHLVCDATHRLLAASPARAASWNADAGTYVGMSLWRFATREIILAEAGLAAAGWFERPFQTLDVRTGANGSREIPVSPGR
MRWETIPLSGGRTGRLTTTLG

Download         Length: 546 bp

>AT123705 NZ_CP039250:c881523-880978 [Sphingopyxis sp. PAMC25046]
ATGACACAGGATCTGCCGATCGGCCGGGCGCTCCGCCGCTTCCGCCGCCTCAACGCCATCAAGCAGGGCCATTTCGCGGA
GCTGCTCGGCGTCGCGCAGGCGAGCGTCTCGCGCTGGGAAAGCGGCACGCACGAGCCCGACGCGGCGCACCGCGAGAAAA
TCGCCGCACTCATCGCCGCGCAGACGGGGAGCGACGCCGATGCCGCGCTCAAACGGTTGGTCGAGACCTCGACGCAGGCG
GTCCACCTCGTCTGTGACGCGACGCACCGCCTGCTCGCGGCGTCGCCCGCGCGCGCGGCGTCGTGGAATGCCGACGCCGG
TACCTATGTCGGCATGTCGCTGTGGCGCTTCGCAACGCGCGAAATCATTCTCGCCGAAGCGGGGCTCGCGGCGGCGGGCT
GGTTCGAGCGCCCGTTCCAGACCCTCGACGTCCGGACCGGCGCCAACGGCAGCCGCGAAATCCCCGTCAGCCCCGGACGG
ATGCGCTGGGAGACCATTCCGCTTTCGGGCGGCCGCACAGGACGCCTGACGACGACGCTTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References