Detailed information of TA system TA123686

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/ElaA-DUF1778
• Location: 1801..2552
• Replicon: plasmid unnamed5
• Accession: NZ_CP039224
• Organism: Piscirickettsia salmonis strain NVI 5692

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: PsalN5692_RS19915
• Protein ID: WP_155069040.1
• Coordinates: 2055..2552 (+)
• Length: 166 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: PsalN5692_RS19910
• Protein ID: WP_155069039.1
• Coordinates: 1801..2067 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PsalN5692_RS19905	1..1071	+	1071	WP_155069038.1	RepB family plasmid replication initiator protein	-
PsalN5692_RS19910	1801..2067	+	267	WP_155069039.1	DUF1778 domain-containing protein	Antitoxin
PsalN5692_RS19915	2055..2552	+	498	WP_155069040.1	GNAT family N-acetyltransferase	Toxin
PsalN5692_RS19920	2601..3464	+	864	WP_155069041.1	KilA-N domain-containing protein	-
PsalN5692_RS19925	3983..5410	-	1428	WP_155069042.1	peptide MFS transporter	-
PsalN5692_RS19930	5651..6262	+	612	WP_155069043.1	2OG-Fe(II) oxygenase	-
PsalN5692_RS19935	6259..7464	+	1206	WP_155069044.1	pyridoxal phosphate-dependent aminotransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..42705	42705

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (30-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-87)

Sequences

Toxin

Protein

• Length: 166 a.a.
• Molecular weight: 18291.45 Da
• Isoelectric Point: 9.4395

>T123686 WP_155069040.1 NZ_CP039224:2055-2552 [Piscirickettsia salmonis]
MGKITPPELLETSHDTRLFNCGDIALNEWLQKRALKNQAADASRVYVVTNSQRVVGYYALASGSVERMIIPGSMTRNMPA
TIPVIVLGRLAVDIDYHDQKLGSGLLKDALTRCVLAADTVAAKAVMVHAISERAKRFYIKNSFVECPEVEMTLFVSIKKI
RQLLI

Nucleotide

• Length: 498 bp

>T123686 NZ_CP039224:2055-2552 [Piscirickettsia salmonis]
TTGGGAAAAATAACACCACCAGAATTATTAGAAACTAGTCACGATACTCGACTTTTTAATTGTGGTGATATTGCTCTCAA
TGAATGGCTACAGAAGCGAGCATTGAAAAATCAGGCCGCTGATGCAAGTAGGGTGTATGTAGTCACTAATAGTCAACGTG
TAGTTGGCTATTATGCTCTGGCTAGTGGGTCTGTAGAGCGAATGATCATACCAGGTTCAATGACTCGCAATATGCCGGCA
ACAATACCTGTAATCGTGTTGGGACGGTTAGCTGTTGATATTGATTATCACGATCAGAAGTTAGGTAGTGGTTTATTAAA
AGATGCTTTGACTCGATGTGTATTAGCTGCTGATACTGTTGCTGCAAAGGCGGTTATGGTTCATGCAATATCAGAAAGAG
CAAAGCGATTTTACATAAAGAATTCCTTTGTTGAATGTCCAGAGGTCGAGATGACCTTGTTTGTTTCAATCAAGAAAATT
AGGCAGCTTCTAATTTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10051.52 Da
• Isoelectric Point: 4.4819

>AT123686 WP_155069039.1 NZ_CP039224:1801-2067 [Piscirickettsia salmonis]
MTKVAPINMRTTAEQFDLLTKAANALNTDRTSFILNIACREAENVLLDRRLFQLTDEGFDAFEVALDEPLTQSEKLKRLL
IEPAPWEK

Nucleotide

• Length: 267 bp

>AT123686 NZ_CP039224:1801-2067 [Piscirickettsia salmonis]
ATGACGAAAGTAGCACCGATAAATATGCGTACAACCGCAGAACAGTTTGACTTACTGACTAAAGCCGCAAATGCATTAAA
TACAGATCGAACCTCATTTATTTTAAATATTGCTTGTCGTGAGGCCGAAAATGTATTGCTAGATCGCCGTTTATTTCAGT
TAACTGATGAGGGTTTTGATGCTTTTGAGGTAGCATTAGATGAGCCATTGACTCAGTCCGAGAAATTGAAACGTTTGTTA
ATCGAGCCTGCTCCTTGGGAAAAATAA