Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2499481..2500114 Replicon chromosome
Accession NZ_CP039143
Organism Acinetobacter sp. 10FS3-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag E5Y90_RS11760 Protein ID WP_174660274.1
Coordinates 2499481..2499864 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag E5Y90_RS11765 Protein ID WP_151204001.1
Coordinates 2499857..2500114 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E5Y90_RS11740 2494811..2497093 - 2283 WP_174660270.1 TRAP transporter large permease subunit -
E5Y90_RS11745 2497273..2497845 - 573 WP_174660271.1 rhombosortase -
E5Y90_RS11750 2497912..2498952 - 1041 WP_174660272.1 hypothetical protein -
E5Y90_RS11755 2499191..2499364 - 174 WP_174660273.1 hypothetical protein -
E5Y90_RS11760 2499481..2499864 - 384 WP_174660274.1 hypothetical protein Toxin
E5Y90_RS11765 2499857..2500114 - 258 WP_151204001.1 succinate dehydrogenase assembly factor 2 Antitoxin
E5Y90_RS11770 2500298..2501470 + 1173 WP_174660275.1 acyl-CoA dehydrogenase family protein -
E5Y90_RS11775 2501528..2503018 - 1491 WP_174660276.1 NAD(P)/FAD-dependent oxidoreductase -
E5Y90_RS11780 2503232..2503597 - 366 WP_151203973.1 50S ribosomal protein L17 -
E5Y90_RS11785 2503617..2504624 - 1008 WP_151203974.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-80)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 15150.24 Da        Isoelectric Point: 9.9479

>T123549 WP_174660274.1 NZ_CP039143:c2499864-2499481 [Acinetobacter sp. 10FS3-1]
MDNRCFRLKRSKCALTFQLFIFAVLMFLLYQLLPLFLWGVCGILGVLIYHLFYHKTPQVEQLEYLDGREWSLSTVKKTYR
VAISHVIDHQAYIVVYFQHAKARPLLIWCDQLPLKQWKSLKVLTKML

Download         Length: 384 bp

>T123549 NZ_CP039143:c2499864-2499481 [Acinetobacter sp. 10FS3-1]
ATGGATAATCGTTGTTTCAGGCTGAAACGCAGTAAATGTGCCCTGACGTTTCAGCTATTTATTTTTGCTGTATTGATGTT
CCTGCTTTACCAGTTATTACCTCTGTTTCTATGGGGTGTATGTGGTATTTTAGGTGTCTTGATTTATCATCTGTTTTACC
ATAAAACTCCGCAGGTTGAACAGTTGGAATATCTGGATGGGCGAGAATGGTCACTCAGCACAGTAAAAAAGACCTATCGT
GTGGCGATTAGTCATGTGATTGATCATCAGGCCTATATCGTGGTGTATTTCCAGCATGCCAAGGCGCGCCCTTTGCTGAT
CTGGTGTGATCAATTGCCGCTAAAACAGTGGAAATCTTTAAAAGTTCTTACAAAAATGTTGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10237.78 Da        Isoelectric Point: 4.4663

>AT123549 WP_151204001.1 NZ_CP039143:c2500114-2499857 [Acinetobacter sp. 10FS3-1]
MTDEISLEERKVIYRARRGLKELDVYFDPYVKNYYLSAEPFEKEMFAELVAQEDPDLLDWFMEVSEPPRPELKAFILKLK
FYVHG

Download         Length: 258 bp

>AT123549 NZ_CP039143:c2500114-2499857 [Acinetobacter sp. 10FS3-1]
ATGACTGATGAAATAAGCTTAGAAGAACGCAAAGTGATTTATCGTGCACGTCGTGGCTTAAAAGAGCTGGATGTGTATTT
TGATCCCTACGTAAAAAACTACTATCTCAGCGCTGAACCTTTTGAAAAAGAAATGTTTGCTGAGCTGGTTGCTCAGGAAG
ATCCGGATCTGCTGGACTGGTTTATGGAAGTGTCGGAACCGCCACGCCCTGAATTGAAAGCCTTTATCCTGAAACTTAAA
TTTTACGTTCATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References